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Table 2 Nine-year outcomes among 469 patients with different immunological risks transplanted with kidneys from living (LD) and deceased donors (DD)

From: Effects of immunotherapy induction on outcome and graft survival of kidney-transplanted patients with different immunological risk of rejection

Variable

LD (n = 255)

DD (n = 214)

G1 (n = 191)

G2 (n = 41)

G3 (n = 12)

G4 (n = 11)

Total

G1 (n = 150)

G2 (n = 34)

G3 (n = 14)

G4 (n = 16)

Total

Rejection episodes

 TCMR

31 (16.23%)

8 (19.51%)

2 (16.67%)

1 (9.09%)

42 (16.47%)

30 (20.00%)

5 (14.71%)

2 (14.29%)

0

37 (17.29%)

 AMR

4 (2.094%)

1 (2.44%)

1 (8.34%)

2 (18.18%)

8 (3.14%)

7 (4.67%)

3 (8.82%)

2 (14.29%)

1 (6.25%)

13 (6.07%)

 TCMR/AMR

0

0

0

 

0

1 (0.67%)

1 (2.94%)

0

0

2 (0.93%)

Graft loss

 TCMR

4 (2.09%)

0

0

0

4 (1.57%)

1 (0.67%)

0

0

0

1 (0.47%)

 AMR

1 (0.53%) ID359: DR7 (2170); DR9 (4081)

0

0

1 (9.09%) ID363: B18 (1342)

2 (0.78%)

0

3 (8.82%)

0

0

3 (1.40%)

ID97: A11 (6612); B44 (15026)

ID233: A1 (815); B52 (1507)

ID290: A23 (1906); B65 (1078); DR1 (1614)

Other causes of graft loss

 Cardiovascular

4 (2.09%)

0

0

0

0

1 (0.67%)

0

0

0

1 (0.47%)

 Infections

12 (6.28%%)

1 (2.44)

0

0

5 (1.96%)

9 (6.00%)

2 (5.88%)

0

1 (6.25%)

4 (1.87%)

 Death

21 (10.99%)

2 (4.88%)

1 (8.33%)

0

20 (7.84%)

20 (13.33%)

10 (29.42%)

2 (14.29%)

3 (18.75%)

32 (14.95%)

 Other

22 (11.52%)

4 (9.76%)

0

0

22 (8.63%)

18 (12.0%)

4 (11.76%)

1 (7.14%)

0

19 (8.88%)

HLA mismatching

 0

34 (17.80%)

8 (19.51%)

4 (33.33%)

0 (0%)

0.128

2 (1.33%)

0

0 (0%)

0 (0%)

0.053

 1–3

90 (47.12%)

21 (51.22%)

6 (50.00%)

9 (81.82%)

91 (60.67%)

23 (67.65%)

11 (78.57%)

4 (25.00%)

 4–6

67 (35.08%)

12 (29.27%)

2 (16.67%)

2 (18.18%)

57 (38.00%)

11 (32.35%)

3 (21.43%)

12 (75.00%)

Creatinine (mean ± SD)

 Months

  1

1.72 ± 1.16

1.44 ± 0.73

1.65 ± 1.42

1.42 ± 0.40

0.468

2.39 ± 1.66

2.44 ± 1.49

2.28 ± 1.88

2.74 ± 1.43

0.854

  3

1.63 ± 1.00

1.28 ± 0.40

1.35 ± 0.41

1.37 ± 0.30

0.107

1.99 ± 1.30

1.86 ± 1.13

1.57 ± 0.62

2.34 ± 1.13

0.411

  6

1.58 ± 0.87

1.24 ± 0.37

1.28 ± 0.27

1.32 ± 0.30

0.066

1.75 ± 0.89

2.06 ± 1.94

1.53 ± 0.44

2.09 ± 0.96

0.320

 Years

  1

1.52 ± 0.76

1.33 ± 0.57

1.21 ± 0.27

1.29 ± 0.49

0.215

1.73 ± 0.93

1.56 ± 0.67

1.42 ± 0.68

1.72 ± 0.57

0.610

  3

1.45 ± 0.55

1.41 ± 0.68

1.13 ± 0.24

1.73 ± 1.42

0.273

1.72 ± 1.18

1.73 ± 1.04

1.41 ± 0.70

1.64 ± 0.40

0.907

  5

1.54 ± 0.83

1.46 ± 0.55

0.99 ± 0.20

1.12 ± 0.34

0.329

1.53 ± 0.77

1.30 ± 0.45

1.25 ± 0.27

1.63 ± 0.46

0.735

  7

1.25 ± 0.50

1.52 ± 0.58

1.05 ± 0.37

0.94 ± 0.72

0.427

–

–

–

–

–

  9

–

–

–

–

–

–

–

–

–

–