Fig. 1

Early focal segmental lesions in IMN patients: a Pure synechia to Bowman’s capsule,with glomerular enlargement;(PASM;original magnification× 400.) b Synechia at the tip area,accompanied with proliferation of mesangial matrix; (PAS;original magnification× 400.) c Segmental thickening of GBM, accompanied with hyperplasia of podocytes (arrow); (PASM;original magnification× 400.) d Proliferation of extracellular matrix of segmental tuft, with slight hyperplasia of podocytes and proliferation of endothelial cells (arrows);(PASM;original magnification× 400.) e Segmental thickening of GBM,accompanied with segmental proliferation of endothelial cell (arrow);(PAS;original magnification× 400.) f Segmental proliferation of extracellular matrix of segmental tuft, with hyperplasia of podocytes and proliferation of endothelial cells.(PASM;original magnification× 400)