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Table 2 Control group and ADPKD group

From: Cardiac function assessed by myocardial deformation in adult polycystic kidney disease patients

 

ADPKD group (n = 110)

Control group (n = 20)

P Value

Demographics

 Age, years

46.1 ± 13.3

46.1 ± 11.0

0.99

 Male gender, n (%)

48 (43.6)

8 (40.0)

0.76

Race, n (%)

 Caucasian

92 (83.6)

17 (85.0)

0.43

 African American

13 (11.8)

1 (5.0)

 

 Asian

5 (4.5)

2 (10.0)

 

Clinical data

 Systolic Blood Pressure, mmHg

126 ± 14

122 ± 14

0.26

 Diastolic Blood Pressure, mmHg

78 ± 10

71 ± 9

0.004

 Estimated GFR, mL/min/1.73m2

60.7 [38.0–88.0]

99.5 [76.5–113.5]

< 0.001

 BMI, kg/m2

28.5 ± 6.6

26.6 ± 3.2

0.21

 HDL cholesterol, mg/dL

50.0 ± 13.7

55.6 ± 15.0

0.10

 LDL cholesterol, mg/dL

105.8 ± 31.8

120.4 ± 34.8

0.07

 Total Cholesterol, mg/dL

178.8 ± 37.1

194.1 ± 37.6

0.09

 Triglycerides, mg/dL

94 [70–121]

84 [58–108]

0.29

 Hemoglobin, g/dL

12.9 ± 1.3

13.9 ± 1.5

0.005

 ACE Inhibitor, n (%)

74 (67.9)

1 (5.0)

< 0.001

 Beta blocker, n (%)

14 (12.8)

0 (0)

0.09

Echocardiographic data

 Left Ventricle Ejection Fraction, %

59.8 ± 3.6

66.1 ± 3.3

< 0.001

 E peak, cm/s

71.0 ± 16.1

77.2 ± 11.6

0.11

 E/e’ ratio

7.2 [6.3–9.1]

6.7 [6.1–7.6]

0.17

 Global Longitudinal Strain, %

−17.9 ± 2.5

−22.0 ± 2.2

< 0.001

 Systolic Strain Rate, s− 1

0.78 ± 0.13

1.05 ± 0.11

< 0.001

 Early Diastolic Strain Rate, s1

0.75 ± 0.19

1.23 ± 0.30

< 0.001

 E/early diastolic strain rate, cm

100.3 ± 31.5

65.2 ± 15.0

< 0.001

 IVSd, cm

0.96 ± 0.15

0.91 ± 0.16

0.28

 LVIDd, cm

4.8 ± 0.5

4.4 ± 0.5

0.01

 LVPWd, cm

0.94 ± 0.14

0.91 ± 0.16

0.36

 Left ventricular mass index, (g/m2)

82.0 ± 21.6

69.1 ± 8.5

0.014

 Left atrial volume index, (mL/m2)

21.3 ± 2.8

23.4 ± 5.1

0.013

  1. IVSd Interventricular septal thickness, LVIDd Left ventricular internal diameter, LVPWd Left ventricular posterior wall, E Peak early filling velocity