From: Cardiac function assessed by myocardial deformation in adult polycystic kidney disease patients
 | ADPKD group (n = 110) | Control group (n = 20) | P Value |
---|---|---|---|
Demographics | |||
 Age, years | 46.1 ± 13.3 | 46.1 ± 11.0 | 0.99 |
 Male gender, n (%) | 48 (43.6) | 8 (40.0) | 0.76 |
Race, n (%) | |||
 Caucasian | 92 (83.6) | 17 (85.0) | 0.43 |
 African American | 13 (11.8) | 1 (5.0) |  |
 Asian | 5 (4.5) | 2 (10.0) |  |
Clinical data | |||
 Systolic Blood Pressure, mmHg | 126 ± 14 | 122 ± 14 | 0.26 |
 Diastolic Blood Pressure, mmHg | 78 ± 10 | 71 ± 9 | 0.004 |
 Estimated GFR, mL/min/1.73m2 | 60.7 [38.0–88.0] | 99.5 [76.5–113.5] | < 0.001 |
 BMI, kg/m2 | 28.5 ± 6.6 | 26.6 ± 3.2 | 0.21 |
 HDL cholesterol, mg/dL | 50.0 ± 13.7 | 55.6 ± 15.0 | 0.10 |
 LDL cholesterol, mg/dL | 105.8 ± 31.8 | 120.4 ± 34.8 | 0.07 |
 Total Cholesterol, mg/dL | 178.8 ± 37.1 | 194.1 ± 37.6 | 0.09 |
 Triglycerides, mg/dL | 94 [70–121] | 84 [58–108] | 0.29 |
 Hemoglobin, g/dL | 12.9 ± 1.3 | 13.9 ± 1.5 | 0.005 |
 ACE Inhibitor, n (%) | 74 (67.9) | 1 (5.0) | < 0.001 |
 Beta blocker, n (%) | 14 (12.8) | 0 (0) | 0.09 |
Echocardiographic data | |||
 Left Ventricle Ejection Fraction, % | 59.8 ± 3.6 | 66.1 ± 3.3 | < 0.001 |
 E peak, cm/s | 71.0 ± 16.1 | 77.2 ± 11.6 | 0.11 |
 E/e’ ratio | 7.2 [6.3–9.1] | 6.7 [6.1–7.6] | 0.17 |
 Global Longitudinal Strain, % | −17.9 ± 2.5 | −22.0 ± 2.2 | < 0.001 |
 Systolic Strain Rate, s− 1 | 0.78 ± 0.13 | 1.05 ± 0.11 | < 0.001 |
 Early Diastolic Strain Rate, s1 | 0.75 ± 0.19 | 1.23 ± 0.30 | < 0.001 |
 E/early diastolic strain rate, cm | 100.3 ± 31.5 | 65.2 ± 15.0 | < 0.001 |
 IVSd, cm | 0.96 ± 0.15 | 0.91 ± 0.16 | 0.28 |
 LVIDd, cm | 4.8 ± 0.5 | 4.4 ± 0.5 | 0.01 |
 LVPWd, cm | 0.94 ± 0.14 | 0.91 ± 0.16 | 0.36 |
 Left ventricular mass index, (g/m2) | 82.0 ± 21.6 | 69.1 ± 8.5 | 0.014 |
 Left atrial volume index, (mL/m2) | 21.3 ± 2.8 | 23.4 ± 5.1 | 0.013 |