Table 3 Subgroup analysis of the associations between 90-day all-cause mortality and the admission serum sodium level
No. of patients/deaths | Admission serum sodium level, mmol/L | P for interaction | |||
|---|---|---|---|---|---|
< 136.0 | 136.0–144.9 | ≥145.0 | |||
Age, years | |||||
< 65 | 5772/956 | 1.36 (1.18, 1.57) | 1.00 | 1.64 (1.25, 2.15) | 0.553 |
≥ 65 | 7687/2139 | 1.41 (1.28, 1.56) | 1.00 | 1.52 (1.29, 1.78) | |
Sex | |||||
Male | 7543/1766 | 1.38 (1.24, 1.54) | 1.00 | 1.53 (1.27, 1.86) | 0.333 |
Female | 6078/1388 | 1.35 (1.19, 1.53) | 1.00 | 1.62 (1.33, 1.98) | |
Creatinine, mg/dl | |||||
< 1.50 | 6295/1345 | 1.55 (1.37, 1.76) | 1.00 | 1.27 (0.98, 1.63) | 0.005 |
≥ 1.50 | 7324/1808 | 1.24 (1.11, 1.39) | 1.00 | 1.59 (1.34, 1.88) | |
Urine output, ml/24 h | |||||
< 1120 | 6487/1943 | 1.31 (1.19, 1.45) | 1.00 | 1.32 (1.11, 1.56) | 0.136 |
≥ 1120 | 6520/1069 | 1.33 (1.16, 1.53) | 1.00 | 1.71 (1.35, 2.17) | |
Vasopressin use | |||||
Yes | 5907/1728 | 1.33 (1.19, 1.48) | 1.00 | 1.49 (1.22, 1.83) | 0.258 |
No | 7714/1426 | 1.42 (1.26, 1.61) | 1.00 | 1.55 (1.28, 1.87) | |
Renal replacement therapy | |||||
Yes | 365/177 | 1.25 (0.91, 1.72) | 1.00 | 1.10 (0.51, 2.40) | 0.683 |
No | 13,265/2977 | 1.38 (1.27, 1.50) | 1.00 | 1.58 (1.37, 1.82) | |