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Fig. 1 | BMC Nephrology

Fig. 1

From: Uric acid regulates NLRP3/IL-1β signaling pathway and further induces vascular endothelial cells injury in early CKD through ROS activation and K+ efflux

Fig. 1

UA induced the expression of IL-1β and ICAM-1 in HUVECs. The cells were treated by UA (5, 10, 20 mg/dL, respectively) for 24 h or UA (6, 12, 24 h, respectively) at 20 mg/dL. a Detection of protein expression of IL-1β in cells supernatant by western blotting; b Measurement of mRNA expression of IL-1β in cells by qPCR; c Measurement of protein expression of ICAM-1 in cells by western blotting. *P < 0.05; **p < 0.01; ***p < 0.001

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