Fig. 2From: A novel single amino acid deletion impairs fibronectin function and causes familial glomerulopathy with fibronectin deposits: case report of a familySuperimposition between the native (white) and mutated (bronze) FN3 domain models. Despite the replacement of the native Ile1988 position with Val1987 in the mutated model, the previous eight residues had their main chain trace completely altered, as well as in other parts of the molecule. Several contacts were lost so that the mutated model is floppierBack to article page