Association of plasma macrophage colony-stimulating factor with cardiovascular morbidity and all-cause mortality in chronic hemodialysis patients

Table 3 Cox regression analyses of the association of the important variables with cardiovascular disease morbidity

Variables	HR	95% CI	p value
Univariate analyses (n = 52)
Sex(M/F)^a	1.084	0.497–2.364	0.840
Age (Y)	1.039	1.013–1.065	0.003
Hb (g/L)	1.016	0.994–1.040	0.159
Predialysis Serum creatinine (μmol/L)	0.999	0.997–1.000	0.117
Predialysis Systolic BP (mmHg)	1.023	1.002–1.044	0.035
Predialysis Diastolic BP (mmHg)	0.982	0.952–1.013	0.257
Predialysis Mean BP (mmHg)	1.005	0.975–1.036	0.754
M-CSF ^b	2.889	1.305–6.398	0.009
Multivariate analyses(n = 52)
M-CSF (adjusted for sex, age, systolic BP)	4.504	1.851–10.959	0.001
M-CSF (adjusted for sex, age, HB)	4.728	1.985–11.264	< 0.001
M-CSF (adjusted for sex, age, serum creatinine)	4.932	2.013–12.082	< 0.001
M-CSF (adjusted for sex, age, Diastolic BP)	4.506	1.894–10.721	0.001

^a Female has been codified as 0 and male as 1
^b M-CSF concentration < 995.99 pg/mL has been codified as 0 and ≥ 995.99 pg/mL as 1
HR Hazard ratio, CI confidence interval, BP blood pressure

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