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Table 1 Demographic and Clinical characteristics of CKD patients

From: Intrarenal microRNA signature related to the fibrosis process in chronic kidney disease: identification and functional validation of key miRNAs

  MCD FSGS DN
Number of cases 10 10 10
Sex (M/F) 6:4 6:4 7:3
Age (year) 26.1 ± 1.5 30.4 ± 2.8 48.6 ± 2.4a, b
Serum creatinine (μmol/l) 65 ± 3.8 173.4 ± 34.9 399.6 ± 64.4a, c
eGFR (ml/min per 1.73 m2) 122.9 ± 4.2 60.3 ± 12.3a 20.0 ± 5.3a, b
24-h proteinuria (g) 5.3 ± 1.1 3.3 ± 1.0 5.0 ± 1.2
Serum albumin (g/L) 18.1 ± 0.3 36.8 ± 3.8a 39.5 ± 1.1a
Percentage of glomerular sclerosis (%) 0.8 ± 0.5 41.1 ± 7.3a 60.3 ± 7.2a, d
Tubulointerstitial fibrosis score 0 2.5 ± 0.2a 2.9 ± 0.1a, d
  1. MCD minimal change disease, FSGS focal segmental glomerulosclerosis, DN diabetic nephropathy, M male, F female, eGFR estimated glomerular filtration rate. a versus MCD p < 0.001, b versus FSGS p < 0.001, c versus FSGS p < 0.01, d versus FSGS p < 0.05
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