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Table 1 Demographic and Clinical characteristics of CKD patients

From: Intrarenal microRNA signature related to the fibrosis process in chronic kidney disease: identification and functional validation of key miRNAs

 

MCD

FSGS

DN

Number of cases

10

10

10

Sex (M/F)

6:4

6:4

7:3

Age (year)

26.1 ± 1.5

30.4 ± 2.8

48.6 ± 2.4a, b

Serum creatinine (μmol/l)

65 ± 3.8

173.4 ± 34.9

399.6 ± 64.4a, c

eGFR (ml/min per 1.73 m2)

122.9 ± 4.2

60.3 ± 12.3a

20.0 ± 5.3a, b

24-h proteinuria (g)

5.3 ± 1.1

3.3 ± 1.0

5.0 ± 1.2

Serum albumin (g/L)

18.1 ± 0.3

36.8 ± 3.8a

39.5 ± 1.1a

Percentage of glomerular sclerosis (%)

0.8 ± 0.5

41.1 ± 7.3a

60.3 ± 7.2a, d

Tubulointerstitial fibrosis score

0

2.5 ± 0.2a

2.9 ± 0.1a, d

  1. MCD minimal change disease, FSGS focal segmental glomerulosclerosis, DN diabetic nephropathy, M male, F female, eGFR estimated glomerular filtration rate. a versus MCD p < 0.001, b versus FSGS p < 0.001, c versus FSGS p < 0.01, d versus FSGS p < 0.05