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Table 2 Mean Hb levels (g/dL) and mean change in hemoglobin from Baseline to EOC – Dialysis, ITT Population (N = 126)

From: Correction to: Efficacy, tolerability and safety of darbepoetin alfa injection for the treatment of anemia associated with chronic kidney disease (CKD) undergoing dialysis: a randomized, phase-III trial

Statistics

ITT Population (N = 126)

PP Population (N = 93)

Darbepoetin alfa (n = 63)

Erythropoietin alfa (n = 63)

Darbepoetin alfa (n = 47)

Erythropoietin alfa (n = 46)

Baseline

 n

56

53

47

46

 Mean (SD)

8.39 (0.90)

8.80 (0.89)

8.39 (0.85)

8.72 (0.91)

End of first evaluation visit

 n

55

51

47

46

 Mean (SD)

10.20 (1.74)

10.61 (1.55)

10.33 (1.42)

10.90 (0.95)

Within group comparison

 p-value#

<.0001

<.0001

<.0001

<.0001

 Mean change

1.84

1.85

1.94

2.18

 95% CI

[1.36–2.32]

[1.37–2.33]

[1.48–2.40]

[1.84–2.53]

Between group comparison

 Mean change

−0.01

−0.24

 95% CI

[−0.68–0.66]

[− 0.81–0.32]

 p-value**

0.9703

0.3985

  1. N number of subject at each visit, N total number of subjects, ITT Intent to treat, PP Per protocol
  2. # p-values were obtained using Paired t Test for mean (two tailed, α 0.05)
  3. ** p-values were obtained using Unpaired t Test for mean change (two tailed, α = 0.05)
  4. Note: Patients taken where Hb < 10 at Screening