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Table 2 Follow-up outcomes of patients who survived the index hospitalization (n = 568)

From: Analysis of survival after initiation of continuous renal replacement therapy in patients with extracorporeal membrane oxygenation

 

Event (%)

Adjusted HR (95% CI), P value

≤ 3 days

4–6 days

≥ 7 days

4–6 days vs. ≤ 3 days

≥ 7 days vs. ≤ 3 days

≥ 7 days vs. 4–6 days

Outcome/model

(n = 247)

(n = 134)

(n = 187)

aHR (95% CI)

P

aHR (95% CI)

P

aHR (95% CI)

P

All-cause mortality

 Model 1

139 (56.3)

78 (58.2)

90 (48.1)

1.12 (0.84–1.49)

0.456

0.97 (0.74–1.28)

0.832

0.87 (0.63–1.20)

0.390

 Model 2

139 (56.3)

78 (58.2)

90 (48.1)

1.19 (0.89–1.60)

0.245

0.94 (0.71–1.25)

0.684

0.79 (0.57–1.10)

0.162

 Model 3

139 (56.3)

78 (58.2)

90 (48.1)

1.15 (0.86–1.55)

0.348

0.91 (0.68–1.22)

0.536

0.79 (0.57–1.10)

0.164

 Model 4

139 (56.3)

78 (58.2)

90 (48.1)

1.16 (0.85–1.57)

0.353

1.001 (0.73–1.38)

0.993

0.87 (0.62–1.22)

0.409

Long-term dialysisa

 Model 1

16 (6.5)

8 (6.0)

17 (9.1)

0.90 (0.34–2.41)

0.831

2.64 (1.29–5.40)

0.008

2.94 (1.14–7.57)

0.025

 Model 2

16 (6.5)

8 (6.0)

17 (9.1)

0.93 (0.33–2.64)

0.890

2.80 (1.33–5.90)

0.007

3.01 (1.11–8.17)

0.030

 Model 3

16 (6.5)

8 (6.0)

17 (9.1)

1.12 (0.40–3.14)

0.834

3.46 (1.47–8.14)

0.005

3.10 (1.03–9.29)

0.044

 Model 4

16 (6.5)

8 (6.0)

17 (9.1)

0.93 (0.34–2.58)

0.891

2.30 (0.78–6.75)

0.131

2.47 (0.76–7.97)

0.131

Ventilator dependenta

 Model 1

23 (9.3)

17 (12.7)

34 (18.2)

1.32 (0.69–2.55)

0.404

2.47 (1.39–4.40)

0.002

1.87 (0.99–3.52)

0.052

 Model 2

23 (9.3)

17 (12.7)

34 (18.2)

1.37 (0.70–2.70)

0.357

2.50 (1.39–4.47)

0.002

1.82 (0.97–3.42)

0.064

 Model 3

23 (9.3)

17 (12.7)

34 (18.2)

1.28 (0.64–2.54)

0.485

2.45 (1.32–4.54)

0.004

1.92 (0.99–3.72)

0.054

 Model 4

23 (9.3)

17 (12.7)

34 (18.2)

1.23 (0.60–2.52)

0.580

1.73 (0.87–3.43)

0.116

1.41 (0.70–2.84)

0.333

Readmissiona

 Model 1

92 (37.2)

47 (35.1)

83 (44.4)

0.88 (0.62–1.26)

0.494

1.43 (1.05–1.94)

0.024

1.62 (1.11–2.36)

0.013

 Model 2

92 (37.2)

47 (35.1)

83 (44.4)

0.86 (0.60–1.26)

0.443

1.43 (1.05–1.94)

0.023

1.65 (1.12–2.44)

0.012

 Model 3

92 (37.2)

47 (35.1)

83 (44.4)

0.85 (0.59–1.24)

0.411

1.43 (1.04–1.96)

0.028

1.67 (1.13–2.47)

0.010

 Model 4

92 (37.2)

47 (35.1)

83 (44.4)

0.82 (0.56–1.20)

0.307

1.08 (0.77–1.51)

0.668

1.31 (0.87–1.98)

0.197

  1. aHR adjusted hazard ratio, CI Confidence interval
  2. Model 1 was adjusted for baseline age, sex, comorbidities listed in Table 1, and study year; Model 2 was further adjusted for baseline monthly income and urbanization level of area of residence; Model 3 was further adjusted for ECMO indication, ECMO volume, and hospital level; Model 4 was further adjusted for in-hospital outcomes, including sepsis, respiratory failure, massive blood transfusion, ECMO duration (days), ventilator days, ICU duration, and hospital stay length;
  3. awas estimated using a subdistribution hazard model, with death being considered as a competing risk
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BMC Nephrology

ISSN: 1471-2369

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