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Table 2 Characteristics and results of the studies assessing physical performance with QOL

From: Physical performance in patients treated with nocturnal hemodialysis - a systematic review of the evidence

Author, year

Country

No. of NHD pts

Frequency of NHD treatment

Study design, control group

Follow-up duration, months

Male %

Age, yearsa

Assessment and outcome

Effects NHD

Self-reported measurements

 Hall, 2012 [22]

USA, Canada

45

6 times/wk., ≥6 h

RCT, CHD controls

12

64

52 ± 14

Physical health composite (PHC) by Short form-36 (SF-36), physical functional subscale (PF)

Change PHC after 12 mo NHD: 2.7 ± 1.4 vs control group: 2.1 ± 1.5, p = 0.75, Change PF after 12 mo NHD: − 3.1 ± 3.5 vs control group: 1.1 ± 3.6, p = 0.40.

 Ok, 2014 [14]

Turkey

247

3 times/wk., 7–8 h

Prospective, non-randomized case-control, CHD controls

12

68

45 ± 14

Physical functioning by SF-36

Described: all dimensions were unchanged in the NHD group. Change in control group: vitality score decreased, 68.7 ± 24.3 to 64.4 ± 25.2, p = 0.01.

 Eps, 2010 [24]

Australia

63

3–5 times/wk., 6–10 h

Prospective cohort, no controls

6–12

79

52 ± 13

Physical functioning by Kidney disease QoL (KD-QoL)

Change in PF after 6–12 mo NHD: 60 to 75, p = 0.003.

 Lockridge, 2004 [25]

Canada

40

5–6 times/wk., 6–10 h

Prospective, longitudinal, no controls

60

65

50 (23–81)

Physical composite score (PCS) by SF-36

Change in overall mean PCS score after 5 yrs. NHD: 35.23 to 44.94, p = 0.007.

 Fong, 2007 [27]

Canada

26

Cross-sectional, PD controls

67

4912

Physical component summary by KD-QoL

PCS in NHD: 55 ± 2.3 vs control group (PD): 52.3 ± 1.8, p = 0.35.

  1. aAge is given as mean ± SD or as median and IQR