Variable | Definition | |
---|---|---|
Variables related to the recipient of the surgery | Year of transplantation | Calendar year of the current transplantation |
Recipient gender | Gender of the recipient | |
Recipient age | Recipient age in years at transplantation | |
Recipient height | Recipient height in centimeters at transplantation | |
Recipient weight | Recipient weight in kilograms at transplantation | |
Duration under renal replacement therapy | Number of days between the first dialysis (hemodialysis and/or peritoneal dialysis) or the first preemptive transplantation and the transplantation | |
Duration on waiting list before the transplantation | Number of days between the registration on the waiting list related to the current transplantation and the transplantation | |
Type of dialysis just before the transplantation | Type of extra renal purification technique just before the transplantation | |
Primary renal disease | Primary cause of renal failure | |
Vascular history | Whether the recipient had a history of vascular disease before transplantation | |
Cardiac history | Whether the recipient had a cardiovascular history before transplantation | |
Cancer history | Whether the recipient had cancer before transplantation | |
Diabetes history | Whether the recipient had diabetes before transplantation | |
Hepatitis history | Whether the recipient had hepatitis B or C before transplantation | |
Recipient CMV serology | Result of the last recipient cytomegalovirus serology before transplantation | |
Recipient EBV serology | Result of the last recipient Epstein-Barr virus serology before transplantation | |
Anti-class I Immunization | Whether anti-HLA (Human Leukocyte Antigen) class I antibodies were detected during the 6 months before transplantation | |
Anti-class II Immunization | Whether anti-HLA (Human Leukocyte Antigen) class II antibodies were detected during the 6 months before transplantation | |
Recipient HIV serology | Result of the last recipient human immunodeficiency virus serology before transplantation | |
Recipient blood group | Blood group of the recipient | |
Induction therapy | Type of induction therapy at transplantation | |
Variables related to donor at surgery | Age at the graft retrieval | Donor age in years at kidney retrieval |
Donor gender | Gender of the donor | |
Type of donor | Whether the transplant came from a living or deceased donor | |
Type of deceased donation | Heart-beating status for the deceased donations | |
Donor cause of death | Indication of the cerebrovascular cause of death of the donor | |
Last donor serum creatinine | Last serum creatinine level in μmol. L− 1 of the donor before graft retrieval | |
Donor CMV serology | Result of the last cytomegalovirus serology of the donor before graft retrieval | |
Donor EBV serology | Result of the last Epstein-Barr virus serology of the donor before graft retrieval | |
Donor blood group | Blood group of the donor | |
Variables related to transplantation at surgery | Cold ischemia time | Time in minutes between the graft retrieval and its reperfusion, the warm ischemia time being excluded |
Number of HLA-A mismatches | Number of mismatches between the donor and the recipient concerning Human Leukocyte Antigen Locus A (HLA-A) | |
Number of HLA-B mismatches | Number of mismatches between the donor and the recipient concerning Human Leukocyte Antigen Locus B (HLA-B) | |
Number of HLA-DR mismatches | Number of mismatches between the donor and the recipient concerning Human Leukocyte Antigen Locus DR (HLA-DR) | |
Rank of transplantation | Rank of the current kidney transplantation, i.e. number of previous kidney transplantations + 1 | |
Variables collected during the post-transplantation period | Recipient weight | Recipient weight in kilograms at 3 months and 6 months post-transplantation, and at each anniversary of the transplantation |
Maintenance immunosuppressive drug (7 subtypes) | Maintenance immunosuppressive drug prescribed at 3 months and 6 months post-transplantation, and at each anniversary of the transplantation. In case of switching, the most recent treatment is indicated. 7 treatments may be indicated: calcineurin inhibitor, mycophenolate mofetil, mycophenolic acid, azathioprine, sirolimus, everolimus and steroids | |
Recipient serum creatinine | Recipient serum creatinine level in μmol. L−1 at 3 months and 6 months post-transplantation, and at each anniversary of the transplantation | |
Recipient daily proteinuria | Recipient proteinuria in g.L−1 at 3 months and 6 months post-transplantation, and at each anniversary of the transplantation | |
Delayed graft function | The need for at least one dialysis session within the first 7 days post-transplantation | |
Time-to-death | Time in days between the surgery and the patient’s death with a functioning graft (death after return-to-dialysis is not considered) | |
Time-to-graft failure | Time in days between the surgery and the definitive return to dialysis or pre-emptive transplantation | |
Time-to-first acute rejection episode | Time in days between the surgery and the first acute rejection episode | |
Maximum follow-up time | Time in days between the surgery and the last known date at which the recipient was alive with a functioning graft |