Table 2 Description of the EKiTE cohort (N = 13,394)
Continuous variables: mean ± sd | Missing data | Total cohort | ||
|---|---|---|---|---|
Categorical variables: number (%) | N | (%) | (N = 13,394) | |
TRANSPLANTATION | ||||
Year of transplantation > 2010 | – | – | 7894 | (58.9%) |
Rank of the graft ≥2 | – | – | 2353 | (17.6%) |
Cold ischemia time (min) | 151 | (1.1) | 661.3 | ±618.6 |
HLA-A mismatches > 1 | 549 | (4.1) | 3075 | (23.9%) |
HLA-B mismatches > 1 | 314 | (2.3) | 5188 | (39.7%) |
HLA-DR mismatches > 1 | 402 | (3.0) | 1799 | (13.8%) |
RECIPIENT | ||||
Male gender | – | – | 8500 | (63.5%) |
Age (years) | – | – | 52.3 | ±14.0 |
Height (centimeters) | 935 | (7.0) | 169.6 | ±9.8 |
Weight (kilograms) | 1290 | (9.6) | 72.0 | ±15.4 |
Dialysis (years) | 368 | (2.7) | 3.4 | ±4.6 |
Duration on waiting list (years) | 3649 | (27.2) | 2.0 | ±2.0 |
Type of dialysis | ||||
No dialysis | 29 | (0.2) | 2159 | (16.2%) |
Hemodialysis | 9580 | (71.7%) | ||
Peritoneal dialysis | 1626 | (12.2%) | ||
Primary renal disease | ||||
Glomerulonephritis | 1910 | (14.3) | 3200 | (27.9%) |
Tubulo interstitial disease | 4035 | (35.1%) | ||
Reno-vascular disease | 1054 | (9.2%) | ||
Diabetes | 1075 | (9.4%) | ||
Other disease and unknown | 2120 | (18.5%) | ||
Vascular history | 33 | (0.2) | 1992 | (14.9%) |
Cardiac history | 96 | (0.7) | 3267 | (24.6%) |
Diabetes history | – | – | 2325 | (17.4%) |
Cancer history | 5 | (0.0) | 1595 | (11.9%) |
Positive CMV serology | 332 | (2.5) | 8722 | (66.8%) |
Positive EBV serology | 5041 | (37.6) | 8096 | (96.9%) |
Positive HIV serology | 1801 | (13.4) | 129 | (1.1%) |
Positive anti-class I HLA antibodies | 2838 | (21.2) | 3797 | (36.0%) |
Positive anti-class II HLA antibodies | 2967 | (22.2) | 3388 | (32.5%) |
Blood group | ||||
O | 7 | (0.0) | 5478 | (40.9%) |
A | 5889 | (44.0%) | ||
B | 1431 | (10.7%) | ||
AB | 589 | (4.4%) | ||
Induction therapy | ||||
No induction | 65 | (0.5) | 802 | (6.0%) |
ATG | 4987 | (37.4%) | ||
Anti-IL2R | 6680 | (50.1%) | ||
Belatacept | 7 | (0.0%) | ||
Other | 853 | (6.4%) | ||
Delayed Graft Function | 1727 | (12.9) | 2703 | (23.2%) |
DONOR | ||||
Age at retrieval (years) | 148 | (1.1) | 52.1 | ±15.8 |
Male gender | 111 | (0.8) | 7283 | (54.8%) |
Type of donor | ||||
Deceased | 74 | (0.6) | 10,855 | (81.5%) |
Living | 2465 | (18.5%) | ||
Type of deceased donor | ||||
Heart beating | 12 | (0.1) | 10,278 | (76.8%) |
Non-heart-beating | 635 | (4.7%) | ||
Non-attributable | 2469 | (18.5%) | ||
Donor cause of death | ||||
Cerebrovascular | 171 | (1.3) | 6146 | (46.5%) |
Other | 4608 | (34.8%) | ||
Non-attributable | 2469 | (18.7%) | ||
Last donor serum creatinine (μmol/L) | 2119 | (15.8) | 84.8 | ±50.3 |
Positive CMV serology | 135 | (1.0) | 7720 | (58.2) |
Positive EBV serology | 4428 | (33.1) | 8518 | (95.0%) |
Blood group | ||||
O | 56 | (0.4) | 6032 | (45.2%) |
A | 5670 | (42.5%) | ||
B | 1192 | (8.9%) | ||
AB | 444 | (3.3%) | ||