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Fig. 3 | BMC Nephrology

Fig. 3

From: PKD1-associated autosomal dominant polycystic kidney disease with glomerular cysts presenting with nephrotic syndrome caused by focal segmental glomerulosclerosis

Fig. 3

Microscopic findings of the second renal biopsy at the age of 23. Glomerular sclerosis had progressed compared to 4 years ago (panels a and c: periodic acid-Schiff stain; panels b and d: periodic acid-methenamine-silver stain). Greater number of segments were adherent to the Bowman’s capsules (panels a and b), some of which endorsed fibrous crescents (panel b). Glomerular collapse and widening of Bowman’s capsules had also progressed and were forming glomerular cysts (panels c and d). Immunofluorescence microscopy demonstrated IgM deposition in segmental sclerotic lesions of the glomeruli (panel e). Electron microscopy revealed diffuse foot process fusion (panel f)

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BMC Nephrology

ISSN: 1471-2369

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