Fig. 1

Histological findings of the first biopsy. a At lower power view, cellular (left upper & lower) and fibrocellular (right lower) crescents are observed (PAM, × 100)

b At high power view, a cellular crescent showing fibrinoid necrosis and focal destruction of Bowman’s capsule with periglomerular inflammatory reaction is observed (TRC, × 400).

c Global immunofluorescent activity for immunoglobulin M can be observed in the mesangium (original magnification × 400). d Electron microscopic examination showing electron-dense deposits in the mesangium (red arrow) with mesangial proliferation (uranyl acetate, original magnification × 2500).