Fig. 4From: Spironolactone ameliorates endothelial dysfunction through inhibition of the AGE/RAGE axis in a chronic renal failure rat modelAdvanced glycation end products (AGEs) stimulated (a) expression of receptors for advanced glycation end products (RAGEs) and inactivated (b) phosphorylation of endothelial nitric oxide synthase (eNOS) in a dose-dependent manner; * any groups compare with the vehicle group, p < 0.05Back to article page