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Fig. 5 | BMC Nephrology

Fig. 5

From: Spironolactone ameliorates endothelial dysfunction through inhibition of the AGE/RAGE axis in a chronic renal failure rat model

Fig. 5

Spironolactone (a) suppresses the receptor for advanced glycation end products (RAGEs) expression induced by advanced glycation end products (AGEs) stimulation and (b) increases the phosphorylation of endothelial nitric oxide synthase (p-eNOS) in a dose-dependent manner. * any groups compared with the vehicle group, p < 0.05; # any groups compared with the AGEs group, p < 0.05

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