| Univariate | Multivariate | ||
---|---|---|---|---|
Hazard Ratio(95%CI) | P value | Hazard Ratio(95%CI) | P value | |
Male gender | 1.594 (0.894-2.843) | 1.594 | Â | Â |
Age≥65yr (versus <65yr) | 3.400 (1.684-6.865) | 0.001 | 2.437 (1.145-5.189) | 0.021 |
Blood hemoglobin <90g/L (versus ≥90g/L) | 2.977 (1.544-5.743) | 0.001 | ||
Serum creatinine≥500 μmol/L (versus<500μmol/L) | 2.172 (1.210-3.898) | 0.009 | 2.207 (1.218-4.000) | 0.009 |
Serum albumin<30g/L (versus ≥30g/L) | 1.601 (0.884-2.899) | 0.120 | ||
General manifestation (Myalgia, Arthritis, Fever≥38°C, Weight loss≥2kg)) | 0.711 (0.397-1.273) | 0.251 | ||
Cutaneous involvement | 0.569 (0.137-2.362) | 0.437 | ||
Involvement of mucous membranes/eyes | 15.627 (3.307-73.844) | 0.001 | ||
Involvement of ear, nose, and throat (ENT) | 0.049 (0.001-117546.266) | 0.687 | ||
Interstitial lung disease | 3.296 (1.750-6.209) | 0.001 | 2.366 (1.199-4.667) | 0.013 |
Alveolar hemorrhage | 1.521 (0.754-3.066) | 0.241 | ||
Cardiovascular involvement | 1.274 (0.569-2.854) | 0.556 | ||
Abdominal involvement | 4.457 (1.064-18.662) | 0.041 | ||
Nervous system involvement | 0.708 (0.300-1.672) | 0.431 | ||
BVAS | 1.114 (1.054-1.177) | <0.001 | ||
Immunosuppressive treatment | 0.661 (0.360-1.214) | 0.182 | ||
Coronary heart disease | 2.164 (1.009-4.643) | 0.047 | ||
Heart failure | 2.935 (1.241-6.941) | 0.014 | ||
Chronic obstructive pulmonary disease | 1.466 (0.454-4.736) | 0.523 | ||
Liver disease | 4.204 (1.006-17.570) | 0.049 | ||
Peptic ulcer | 1.316 (0.469-3.691) | 0.601 | ||
Diabetes | 1.522 (0.644-3.598) | 0.339 |