Skip to main content

Table 2 Univariate and multivariate Cox proportional hazard regression analysis for patient mortality

From: Clinical characteristics and outcomes in microscopic polyangiitis patients with renal involvement: a study of 124 Chinese patients

 

Univariate

Multivariate

Hazard Ratio(95%CI)

P value

Hazard Ratio(95%CI)

P value

Male gender

1.594 (0.894-2.843)

1.594

  

Age≥65yr (versus <65yr)

3.400 (1.684-6.865)

0.001

2.437 (1.145-5.189)

0.021

Blood hemoglobin <90g/L (versus ≥90g/L)

2.977 (1.544-5.743)

0.001

Serum creatinine≥500 μmol/L (versus<500μmol/L)

2.172 (1.210-3.898)

0.009

2.207 (1.218-4.000)

0.009

Serum albumin<30g/L (versus ≥30g/L)

1.601 (0.884-2.899)

0.120

General manifestation (Myalgia, Arthritis, Fever≥38°C, Weight loss≥2kg))

0.711 (0.397-1.273)

0.251

Cutaneous involvement

0.569 (0.137-2.362)

0.437

Involvement of mucous membranes/eyes

15.627 (3.307-73.844)

0.001

Involvement of ear, nose, and throat (ENT)

0.049 (0.001-117546.266)

0.687

Interstitial lung disease

3.296 (1.750-6.209)

0.001

2.366 (1.199-4.667)

0.013

Alveolar hemorrhage

1.521 (0.754-3.066)

0.241

Cardiovascular involvement

1.274 (0.569-2.854)

0.556

Abdominal involvement

4.457 (1.064-18.662)

0.041

Nervous system involvement

0.708 (0.300-1.672)

0.431

BVAS

1.114 (1.054-1.177)

<0.001

Immunosuppressive treatment

0.661 (0.360-1.214)

0.182

Coronary heart disease

2.164 (1.009-4.643)

0.047

Heart failure

2.935 (1.241-6.941)

0.014

Chronic obstructive pulmonary disease

1.466 (0.454-4.736)

0.523

Liver disease

4.204 (1.006-17.570)

0.049

Peptic ulcer

1.316 (0.469-3.691)

0.601

Diabetes

1.522 (0.644-3.598)

0.339