Table 1 Demographic characteristics of varying stages of chronic kidney disease
Variables | Stage 1,2a | Stage 3Ab | Stage 3Bc | Stage 4,5d | p value | Post hoc |
|---|---|---|---|---|---|---|
|  | n = 23 | n = 28 | n = 31 | n = 42 |  |  |
Age (year) | 47.1 ± 12.7 | 53.6 ± 9.4 | 54.9 ± 10.5 | 58.7 ± 6.1 | 0.002* | a < c,d |
Gender (M/F) | 3/20 | 8/20 | 22/9 | 29/13 | 0.212 | Â |
Hypertension (%) | 42% | 37% | 59% | 54% | 0.191 | Â |
Diabetes mellitus (%) | 12% | 11% | 23% | 54% | 0.160 | Â |
Systolic blood pressure (mm Hg) | 138 ± 18 | 144 ± 28 | 138 ± 24 | 142 ± 15 | 0.943 |  |
Diastolic blood pressure (mm Hg) | 90 ± 15 | 91 ± 4 | 84 ± 18 | 84 ± 12 | 0.784 |  |
BMI (kg/m2) | 27.8 ± 5.4 | 28.2 ± 6.1 | 26.2 ± 6.1 | 24.8 ± 4.3 | 0.172 |  |
BUN (mg/dL) | 14.3 ± 4.4 | 17.7 ± 3.8 | 31.4 ± 13.0 | 64.5 ± 27.1 | <0.001** | a,b < c < d |
eGFR (ml/min/1.73 m^2) | 84.4 ± 20.2 | 52.1 ± 4.4 | 31 ± 9.6 | 11.5 ± 7.3 | <0.001** | a > b > c > d |
Phosphate (mg/dL) | 3.5 ± 0.4 | 3.5 ± 0.6 | 4.0 ± 0.7 | 5.0 ± 1.1 | <0.001** | a,b,c < d |
Cholesterol (mg/dL) | 198.3 ± 50.4 | 171.5 ± 31.8 | 196.6 ± 47.3 | 153.3 ± 44.5 | 0.001** | a,c > d |
HDL-C (mg/dL) | 47.8 ± 14.3 | 43.3 ± 9.8 | 46.1 ± 12.6 | 46.7 ± 21.2 | 0.677 |  |
LDL-C (mg/dL) | 118.2 ± 45.3 | 104.6 ± 31.4 | 114.9 ± 41.3 | 80.8 ± 26.7 | 0.040* | c > d |
Fasting Glucose (mg/dL) | 118.3 ± 46.1 | 106 ± 21.8 | 112.6 ± 43.5 | 94.9 ± 24.6 | 0.263 |  |
HbA1C (%) | 6.3 ± 1.4 | 6.0 ± 0.6 | 6.2 ± 1.1 | 6.1 ± 0.9 | 0.778 |  |
Urine A/C ratio (mg/g) | 438.0 ± 826.4 | 535.7 ± 1018.4 | 2121.3 ± 2540.7 | 1548.0 ± 2377.2 | 0.058 |  |
WBC (×103/μL) | 7.1 ± 2.4 | 6.2 ± 1.9 | 6.4 ± 2.1 | 6.8 ± 2.0 | 0.323 |  |
Uric Acid (mg/dL) | 7.1 ± 1.2 | 7.0 ± 1.4 | 7.5 ± 2.6 | 7.0 ± 1.2 | 0.629 |  |
Platelet(×103/μL) | 230.2 ± 72.6 | 209.2 ± 59.5 | 201.9 ± 51.1 | 195.1 ± 58.2 | 0.159 |  |