Skip to main content

Table 3 The difference of baseline parameters between favorable and unfavorable renal outcome at 6 months

From: Urinary cell-free mitochondrial and nuclear deoxyribonucleic acid correlates with the prognosis of chronic kidney diseases

 

Favorable renal outcome

(n = 53)

Unfavorable renal outcome

(n = 70)

P value

Plasma cf-mtDNA (GE/mL)

441.1 ± 525.6

370.6 ± 641.9

0.538

Plasma cf-nDNA (GE/mL)

760.9 ± 732.9

554.1 ± 850.9

0.184

Urine cf-mtDNA (GE/mL)

0.489 ± 0.751

3.745 ± 12.197

0.027*

Urine cf-nDNA (GE/mL)

1.764 ± 2.388

15.119 ± 40.791

0.009*

MCN (per cell)

87.21 ± 69.40

101.55 ± 95.75

0.356

Urine 8-OH dG/Cr

3.62 ± 2.44

4.03 ± 2.44

0.346

NGAL (ng/mL)

585.24 ± 251.62

780.85 ± 391.39

0.032*

  1. *P < 0.05, Student’s test
  2. MCN, mitochondrial copy number; NGAL, neutrophil gelatinase-associated lipocalin; 8-OH dG, 8-hydroxy-2-deoxyguanosine; cf-mtDNA, cell-free mitochondrial DNA; cf-nDNA, cell-free nuclear DNA; GE/mL, genome equivalents /mL
  3. Favorable renal outcome indicated eGFR at 6 months minus baseline eGFR> = 0; unfavorable renal outcome indicated eGFR at 6 months minus baseline eGFR <0