In search of potential predictors of erythropoiesis-stimulating agents (ESAs) hyporesponsiveness: a population-based study

Table 3 Multivariate binary logistic regression to evaluate non responsiveness to ESAs between the 2nd and the 6th month after ID in CKD patients

	Non responsiveness ΔHb < 0 g/dL (at least once)
	OR (95% CI)	P-value
Baseline Hb (g/dL)	1.7 (1.2–2.2)	< 0.001
Comorbidities
Hypertension	0.8 (0.3–1.7)	0.513
Concomitant drugs
Iron preparations	0.3 (0.2–0.7)	0.002
Folic acid	0.5 (0.2–1.1)	0.100
High dosage ACE inhibitors/ARBs	0.5 (0.3–0.9)	0.022
Laboratory Values
CRP	1.2 (1.0–1.5)	0.060

Transferrin saturation covariate was excluded because of the high proportion of missing values (> 50%)
CKD ESA users starting the treatment at baseline Hb ≥ 11 g/dL were excluded
ACE angiotensin converting enzyme, CRP C-reactive protein

ISSN: 1471-2369