PATIENT CHARACTERISTICS AND OUTCOMES | Total | No AKI/mild AKI | Severe AKI | p |
---|---|---|---|---|
N | 100 (100%) | 41 (41%) | 59 (59%) | < 0.0001 |
Baseline Characteristics | ||||
Age | 58 (12) | 57 (12) | 53 (12) | 0.01 |
Gender (Male) | 64 (64%) | 27 (42%) | 37 (58%) | 0.75 |
BMI | 26 (4) | 26 (4) | 26.5 (5) | 0.65 |
Non caucasian | 14 (14%) | 05 (36%) | 09 (64%) | 0.11 |
MELD functional | 15 (11–19) | 14 (10–17) | 16 (12–22) | 0.01 |
MELD LT | 29 (29–29) | 29 (29–29) | 29 (29–32) | 0.96 |
Liver Disease | ||||
hepatitis C | 46 (46%) | 17(37%) | 29(63%) | 0.44 |
Alcoholic cirrhosis | 13 (13%) | 06(46%) | 07(54%) | 0.68 |
Cryptogenic cirrhosis | 12 (12%) | 05(42%) | 07(58%) | 0.96 |
acute hepatitis | 06 (06%) | 03(50%) | 03(50%) | 0.64 |
hepatitis B | 04 (04%) | 02(50%) | 02(50%) | 0.70 |
Other | 19 (19%) | 08(42%) | 11(57%) | 0.91 |
Comorbidities | ||||
Hypertension | 33(33%) | 12(36%) | 21(64%) | 0.43 |
Diabetes mellitus | 28 (28%) | 14 (50%) | 14 (50%) | 0.26 |
Kidney function | ||||
baseline sCr | 0.77 (0.63–0.99) | 0.77 (0.62–0.98) | 0.77 (0.65–1.00) | 0.87 |
reference sCr | 0.78 (0.62–1.02) | 0.77 (0.64–1.02) | 0.80 (0.61–1.00) | 0.96 |
Estimated GFR (CKD-EPI) by Scr ref. | 78.65 (52–99) | 93.50 (64–105) | 69.40 (45–98) | 0.013 |
Estimated GFR (CKD-EPI) by Scr base | 99.65 (74–110) | 99.25 (75–108) | 108.52 (69–117) | 0.67 |
Urine output first day after LT | 475 (45) | 608 (79) | 383 (49) | 0.01 |
Fluid balance first day after LT | + 1535 (+ 500–2315) | + 1010 (+ 367–1782) | + 1655 (+ 890–2447) | 0.008 |
Severity score indices | ||||
SAPS | 64 (60–72) | 64 (11) | 69 (15) | 0.68 |
SOFA | 13 (11–15) | 12 (10–13) | 14 (12–16) | 0.001 |
process of care | ||||
Anesthesia time | 09:56 (01:59) | 09:08 (01:33) | 10:32 (02:04) | < 0.0001 |
HEPATECTOMY TIME (HH:MM) | 03:11 (00:54) | 02:54 (00:46) | 03:27 (00:57) | 0.003 |
warm ischemia time (HH:MM) | 00:42 (1:11) | 00:41 (1:21) | 00:43 (1:52) | > 0.0001 |
cold ischemia time (HH:MM) | 06:04 (01:55) | 05:49 (02:06) | 06:14 (01:46) | 0.73 |
Red blood cELLS (unit) | 2.39 (2.8) | 1.45 (2.57) | 3 (2.9) | 0.002 |
outcomes | ||||
Time with vasoactive drugs (days) | 2 (1.78) | 1(1.18) | 2 (2) | 0.01 |
Days of Mechanical ventilation | 2 (1.82) | 1 (0.57) | 3 (2) | < 0.0001 |
Lenght of ICU stay (days) | 9.81 (13) | 5.59 (6.3) | 12.75 (2) | 0.003 |
Lenght of hospital stay (days) | 29 (28) | 19.17 (14.6) | 36 (4.2) | < 0.0001 |
Need for Retransplant | 11 (11%) | 01 (09%) | 10 (91%) | 0.02 |
Need for RRT | 36 (36%) | 04 (10.5%) | 34 (89.5%) | < 0.0001 |
60 day Mortality | 21 (21%) | 03 (14.3%) | 18 (85.7%) | 0.004 |