Early detection of acute kidney injury in the perioperative period of liver transplant with neutrophil gelatinase-associated lipocalin

Table 3 Multivariable logistic models with PNGAL and UNGAL for AKI, need for RRT and mortality

VARIABLES	model pngal OR (IC 95%)	P	model ungal OR (IC 95%)	p
AKI
Age (years)	0.9 (0.92–1.02)	0.25	0.98 (0.93–1.02)	0.4
duration anesthesia (hours)	1.54 (1.08–2.20)	0.16	1.61 (1.14–2.27)	0.007
Urine output first day after LT (ml)	0.99 (0.99–1.00)	0.28	26.5 (5)	0.65
Fluid balance first day after LT (ml)	1.00 (1.00–1.00)	0.07	0.99 (0.99–1.00)	0.12
sofa	1.12 (0.91–1.38)	0.27	16 (12–22)	0.01
ngal (ng/ml)	4.72 (0.87–25.39)	0.07	7.87 (1.2–39.70)	0.02
need rrt
duration anesthesia (hours)	1.11 (0.79–1.56)	0.52	1.11 (0.75–1.69)	0.58
Urine output first day after LT (ml)	0.99 (0.99–0.99)	< 0.001	0.99 (0.99–0.99)	0.001
Fluid balance first day after LT (ml)	1.00 (1.00–1.00)	0.22	1.00 (1.00–1.00)	0.36
sofa	1.48 (1.13–1.94)	0.004	1.49 (1.10–2.02)	0.009
ngal (ng/ml)	2.74 (1.35–5.52)	0.005	35.28 (2.8–444)	0.006
MORTALITY
duration anesthesia (hours)	1.48 (1.08–2.09)	0.01	21(64%)	0.43
MELD	1.00 (0.88–1.13)	0.95	14 (50%)	0.26
sofa	1.72 (1.23–2.42)	0.002	1.62 (1.16–2.26)	0.004
ngal (ng/ml)	2.20 (0.33–15)	0.41	6.10 (0.66–56)	0.11

AKI (acute kidney injury), OR (odds ratio), MELD (model for end-stage liver disease), SOFA (Sequential Organ Failure Assessment), RRT (renal replacement therapy)

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