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Fig. 4 | BMC Nephrology

Fig. 4

From: Superagonistic CD28 protects against renal ischemia injury induced fibrosis through a regulatory T-cell expansion dependent mechanism

Fig. 4

Effects of CD28sa on extracellular matrix deposition and oxidative stress in the kidneys. a. Immunochemistry for fibronectin (original magnification × 200, Bar = 100 μM). b. Immunochemistry for collagen IV (original magnification × 200, Bar = 100 μM). c. Immunochemistry for 8-OHdg (original magnification × 200, Bar = 100 μM). d-f. Quantitative statistics of fibronectin, 8-OHdg, and collagen IV deposition proportions in the kidney sections of different groups. *P < 0.05 compared with IR group (n = 6). #P < 0.05 compared with CD28sa-IR group (n = 6)

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