Vitamin e-loaded membrane dialyzers reduce hemodialysis inflammaging

BMC Nephrology

Table 4 NO serum levels (μmol/l) in controls and hemodialyzed patients at the end of a 3 − month period long interdialytic interval HD session. During the same hemodialysis treatment blood was also drawn simultaneously, 60 min after the beginning, from both arterial and venous blood lines

	End long interdialytic interval^#	60 − min Arterial HD line	60 − min Venous HD line
CON	40.3 ± 15.5^	N/A	N/A
BHD	88.4 ± 24.7*	85.2 ± 26.9*	105.2 ± 34.3
VIT-E	70.6 ± 16.9	65.4 ± 21.6**	50.6 ± 32.4
HDF	91.5 ± 38.0*	87.7 ± 31.2*	97.1 ± 42.8

NO, nitric oxide; HD, hemodialysis; ^#, values at the beginning of the last HD session after a 3 − month trial period; 60 − min arterial HD line, NO serum levels from blood sampled from the arterial HD blood line 60 min after the beginning of a long interdialytic interval HD session at the end of the 3 − month trial period; 60 − min venous HD blood line, NO serum levels from blood taken from the venous HD blood line contemporarily drawn 60 min after the beginning of the last 3 − month period long interdialytic interval HD session; CON, hospital staff healthy volunteers; N/A, not applicable; BHD, standard low−flux bicarbonate HD with polysulfone membrane dialyzer; VIT − E, BHD with vitamin E − loaded polysulfone membrane (Excebrane®) dialyzer; HDF, hemodiafiltration with polysulfone membrane dialyzer; ^, P < 0.01 vs all HD treatments; *, P < 0.05 vs VIT − E HD; data are M ± SD; **, P < 0.05 vs VIT − E 60 − min venous HD blood line from samples taken during the same HD session

ISSN: 1471-2369