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Table 3 Structural ECM proteins identified in our study sorted by fold change between IgAN and control patients

From: Characterization of glomerular extracellular matrix in IgA nephropathy by proteomic analysis of laser-captured microdissected glomeruli

Protein name

Gene Name

Uniprot ID

IgAN total vs control

IgA progr vs IgA non-progr

   

Fold change

P-value

Fold change

P-value

Periostin

POSTN

Q15063

3.28

0.000001

1.79

0.04

EGF-containing fibulin-like extracellular matrix protein 1

EFEMP1

Q12805

1.89

0.002

1.08

0.98

Fibrinogen beta chain

FGB

P02675

1.87

0.001

1.10

0.71

Vitronectin

VTN

P04004

1.87

0.00001

1.16

0.18

Transforming growth factor-beta-induced protein ig-h3

TGFBI

Q15582

1.80

0.001

1.13

0.65

Extracellular matrix protein 1

ECM1

Q16610

1.78

0.0003

1.30

0.70

Fibulin-5

FBLN5

Q9UBX5

1.76

0.002

0.70

0.85

Netrin-G1

NTNG1

Q9Y2I2

−1.17

0.03

1.19

0.80

Fibrinogen-like protein 1

FGL1

Q08830

1.60

0.04

1.69

0.045

Fibrinogen gamma chain

FGG

P02679

1.53

0.005

0.93

0.61

EMILIN-1

EMILIN1

Q9Y6C2

1.34

0.005

1.06

0.47

  1. Only proteins significantly changed between IgAN and controls are shown. Full protein list is shown in Additional file 4: Table S3