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Table 1 Characteristics of 46 cases of renal amyloidosis

From: Pattern of renal amyloidosis in South Africa

 AAALp valueTotal
Number of cases, n (%)20 (43)26 (57) 46 (100)
Age (years) at diagnosis, median (IQR)42 (31–51)58 (50–66)< 0.00151 (41–62)
Sex, n (%)  0.74 
 Male9 (45)13 (50) 22 (48)
 Female11 (55)13 (50) 24 (52)
Ethnicity, n (%)  0.03 
 African10 (50)7 (27) 17 (37)
 White07 (27) 7 (15)
 Mixed race10 (50)12 (46) 22 (48)
Presentation, n (%)  0.59 
 Nephrotic syndrome8 (40)14 (54) 22 (48)
 Nephrotic syndrome and renal failure (serum creatinine > 120 μmol/L)9 (45)8 (31) 17 (37)
 Renal failure without nephrotic syndrome3 (15)4 (15) 7 (15)
Laboratory Features, median (IQR)
 Serum creatinine (μmol/L)276 (68.5–882.5)88.5 (82–244)0.52172 (81–385)
 Degree of proteinuria (g/day)9.7 (5.1–17.6)6.2 (4.8–8.2)0.196.76 (4.9–12.0)
 Serum albumin (g/L)18 (16.0–20)23.5 (18–31)0.0319 (16–29)
 Serum total cholesterol (mmol/L))6.12 (5.14–7.8)8.80 (6.60–12.17)0.017.45 (5.9–11.6)
HIV Status, n (%)  0.15 
 Positive2 (10)0 (0) 2 (4)
 Negative15 (75)18 (69) 33 (72)
 Unknown3 (15)8 (31) 11 (24%)
Outcomes
 Survival after diagnosis (months), median (IQR)1 (0.75–1.25)9 (1.5–15)0.022 (1–10)
  1. Abbreviations: AA Secondary amyloidosis, AL Primary amyloidosis, HIV Human immunodeficiency virus, IQR interquartile range
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