AA | AL | p value | Total | |
---|---|---|---|---|
Number of cases, n (%) | 20 (43) | 26 (57) | 46 (100) | |
Age (years) at diagnosis, median (IQR) | 42 (31–51) | 58 (50–66) | < 0.001 | 51 (41–62) |
Sex, n (%) | 0.74 | |||
Male | 9 (45) | 13 (50) | 22 (48) | |
Female | 11 (55) | 13 (50) | 24 (52) | |
Ethnicity, n (%) | 0.03 | |||
African | 10 (50) | 7 (27) | 17 (37) | |
White | 0 | 7 (27) | 7 (15) | |
Mixed race | 10 (50) | 12 (46) | 22 (48) | |
Presentation, n (%) | 0.59 | |||
Nephrotic syndrome | 8 (40) | 14 (54) | 22 (48) | |
Nephrotic syndrome and renal failure (serum creatinine > 120 μmol/L) | 9 (45) | 8 (31) | 17 (37) | |
Renal failure without nephrotic syndrome | 3 (15) | 4 (15) | 7 (15) | |
Laboratory Features, median (IQR) | ||||
Serum creatinine (μmol/L) | 276 (68.5–882.5) | 88.5 (82–244) | 0.52 | 172 (81–385) |
Degree of proteinuria (g/day) | 9.7 (5.1–17.6) | 6.2 (4.8–8.2) | 0.19 | 6.76 (4.9–12.0) |
Serum albumin (g/L) | 18 (16.0–20) | 23.5 (18–31) | 0.03 | 19 (16–29) |
Serum total cholesterol (mmol/L)) | 6.12 (5.14–7.8) | 8.80 (6.60–12.17) | 0.01 | 7.45 (5.9–11.6) |
HIV Status, n (%) | 0.15 | |||
Positive | 2 (10) | 0 (0) | 2 (4) | |
Negative | 15 (75) | 18 (69) | 33 (72) | |
Unknown | 3 (15) | 8 (31) | 11 (24%) | |
Outcomes | ||||
Survival after diagnosis (months), median (IQR) | 1 (0.75–1.25) | 9 (1.5–15) | 0.02 | 2 (1–10) |