Table 1 A comparison of baseline characteristics between patients with a history of stroke at recruitment and those without
Stroke at recruitment | |||
|---|---|---|---|
No N = 2833 | Yes N = 227 | p-value (stroke at recruitment v no stroke at recruitment) | |
Count (Column%) | Count (Column%) | ||
Age (years) | 66 (54–75) | 70 (65–77) | 0.000 |
Male Gender | 1750 (61.8%) | 162 (71.4%) | 0.004 |
Hemiplegic | 65 (28.6%) | ||
Living alone | 571 (20.2%) | 45 (19.8%) | 0.882 |
Widowed | 399 (14.1%) | 39 (17.2%) | 0.302 |
Ethnic group | |||
Caucasian | 2717 (95.9%) | 222 (97.8%) | 0.376 |
Non-Caucasian | 116 (4.1%) | 5 (2.2%) | |
Aetiology of Renal Disease | |||
Renovascular Disease/Hypertension | 811 (28.6%) | 105 (46.3%) | 0.000 |
Diabetic kidney disease | 455 (16.1%) | 49 (21.6%) | 0.031 |
Glomerulonephritis/Vasculitis | 467 (16.5%) | 19 (8.4%) | 0.001 |
Pyelonephritis | 154 (5.4%) | 6 (2.6%) | 0.069 |
Autosomal dominant Polycystic Kidney Disease | 136 (4.8%) | 11 (4.8%) | 0.976 |
Other/Unknown | 810 (28.6%) | 37 (16.3%) | 0.000 |
Smoking historya | 1832 (69.3%) | 169 (80.1%) | 0.001 |
Diabetes | 912 (32.2%) | 101 (44.5%) | 0.000 |
Systolic Blood pressure (mmHg)b | 139 (124–154) | 142 (129–155) | 0.737 |
Diastolic Blood Pressure (mmHg)b | 73 (65–80) | 71 (62–80) | 0.091 |
Hypertensionc | 2541 (90.2%) | 217 (95.6%) | 0.004 |
Myocardial infarction | 432 (15.2%) | 60 (26.4%) | 0.000 |
Heart failured | 516 (18.9%) | 64 (29.1%) | 0.000 |
Peripheral vascular disease | 377 (13.3%) | 56 (24.7%) | 0.000 |
Atrial fibrillation | 178 (6.3%) | 32 (14.1%) | 0.000 |
Medications | |||
Antiplatelete | 1113 (40.1%) | 157 (69.8%) | 0.000 |
Dual antiplatelete | 66 (2.4%) | 20 (8.9%) | 0.000 |
Anticoagulatione | 242 (8.7%) | 29 (12.9%) | 0.036 |
Antiplatelet and Anticoagulante | 35 (1.3%) | 6 (2.7%) | 0.081 |
Statine | 1644 (59.3%) | 174 (77.3%) | 0.000 |
RAS blockadee | 1735 (62.5%) | 136 (60.4%) | 0.532 |
eGFR (mL/min/1.73m2) | 29.5 (19.2–42.2) | 25.2 (16.6–35.5) | 0.000 |
Haemoglobin (g/l)f | 123.0 (112.0–135.0) | 122.0 (111.0–133.0) | 0.423 |
Ferritin (ug/l)g | 107.0 (52.0–207.0) | 108 (46.0–222.0) | 0.824 |
Folate (ug/l)h | 7.6 (5.7–10.2) | 8.0 (5.9–9.2) | 0.600 |
Vitamin B12 (ng/L)i | 418 (311–563.0) | 414.5 (351–486.0) | 0.895 |
Albumin (g/l)j | 43 (40–45) | 42 (39–44) | 0.002 |
Corrected Calcium (mmol/l)k | 2.30 (2.21–2.39) | 2.30 (2.21–2.39) | 0.501 |
Phosphate (mmol/l)l | 1.12 (0.98–1.28) | 1.12 (0.98–1.30) | 0.914 |
Parathyroid Hormone (ng/l)m | 63.5 (37.0–111.0) | 64.0 (43.0–123.0) | 0.147 |
Total Cholesterol (mmol/l)n | 4.5 (3.7–5.3) | 4.2 (3.7–5.0) | 0.005 |
HDL Cholesterol (mmol/l)o | 1.3 (1.1–1.6) | 1.2 (1.0–1.5) | 0.001 |
LDL Cholesterol (mmol/l)p | 2.1 (1.6–2.8) | 2.2 (1.7–2.9) | 0.652 |
Triglycerides (mmol/l)q | 1.5 (1.0–2.3) | 1.5 (1.1–2.4) | 0.649 |
Bicarbonate (mmol/l)r | 23.5 (20.9–26.1) | 23.0 (18.8–24.5) | 0.091 |
C Reactive Protein (mg/l)s | 3.8 (1.7–8.3) | 4.3 (2.1–9.7) | 0.091 |
Urine Protein Creatinine Ratio (g/mol)t | 33.9 (13.7–113.3) | 34.8 (15.0–111.1) | 0.401 |