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Table 3 Multivariable Cox regression analysis: stroke at recruitment and all-cause mortality, ESRD and NFCVE

From: Impact of prior stroke on major clinical outcome in chronic kidney disease: the Salford kidney cohort study

 

All-cause mortality

ESRD

NFCVE

HR (95%CI)

p-value

HR (95%CI)

p-value

HR (95%CI)

p-value

Univariate model

1.79 (1.52–2.11)

0.000

1.50 (1.21–1.86)

0.000

2.73 (2.07–3.60)

0.000

Model 1

1.45 (1.23–1.71)

0.000

1.53 (1.24–1.91)

0.000

2.25 (1.70–2.97)

0.000

Model 2

1.34 (1.13–1.58)

0.001

1.38 (1.11–1.72)

0.004

2.17 (1.64–2.88)

0.000

Model 3

1.17 (0.99–1.39)

0.065

1.32 (1.05–1.65)

0.017

1.59 (1.17–2.15)

0.002

Model 4

1.20 (1.00–1.43)

0.050

1.34 (1.06–1.69)

0.016

1.54 (1.12–2.11)

0.011

  1. Model 1: Adjusted for age, gender
  2. Model 2: Adjusted for model 1 plus recruitment eGFR (CKD-EPI)
  3. Model 3: Adjusted for model 2 plus diabetes, myocardial infarction, heart failure, peripheral vascular disease, hypertension and atrial fibrillation
  4. Model 4: Adjusted for model 3 plus smoking history