Table 1 Baseline characteristics of all patients admitted to the ICU

 Mean age, years^a (SD)

42.5 (16.8)

43.7 (16.8)

40.9 (16.6)

 Male gender^a %

58.9

61.2

55.7

 Black African

58.0

60.5

54.3

 Mixed Ancestry

27.4

26.0

29.6

 BCaucasian

13.8

12.7

15.3

 Other

0.8

0.8

0.8

 Diabetes^a %

13.2

16.1

9.1

 Mean HbA1c % (SD)

9.9 (3.2)

10.3 (3.1)

9.1 (3.3)

 Hypertension^a %

31.6

32.2

30.7

 Ischaemic heart disease %

4.2

4.6

3.7

 Active Tuberculosis %

6.1

6.6

5.4

 Chronic kidney disease^a %

7.7

6.4

9.4

 Mean CKD eGFR (SD)

32 (19)

40 (16)

21 (1)

 Epilepsy %

4.8

5.0

4.6

 Malignancy^a %

3.3

3.6

2.8

 Positive, n (%)

155 (32.6)

105 (35.1)

50 (28.3)

 Negative, n (%)

321 (67.4)

194 (64.9)

127 (71.8)

 Median CD4 count, cells/μL (IQR)

318(156–493)

205 (119–391)

404 (308–513)

 Median viral load, log (IQR)

2.0 (1.98–4.04)

2.0 (1.88-3.62)

2.5 (2.00–4.64)

 Receiving HAART^a %

11.9

14.5

8.2

 Emergency admissions %

87.0

92.8

79.0

 Mean SAPS 3 score^a (SD)

48.1

54.0

39.7

 Median highest SOFA score^a (IQR)

4 (1–6)

6 (3–9)

2 (1–4)

 Sepsis and septic shock^a %

30.2

43.1

11.9

 Ventilated^a %

53.7

64.8

38.2

 median ventilator days (IQR)

3 (1–7)

3 (1–8)

2 (1–4)

 Required vasopressors^a %

25.0

38.8

5.4

 ARDS^a %

4.4

6.8

0.9

 Median ICU days (IQR)

3 (1–6)

4 (2–8)

2 (1–4)

 ICU length of stay > 7 days^a %

24.7

33.2

12.8

 Deceased in ICU %

13.0

20.5

2.3