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Table 3 Effect of curcumin treatment on liver weight and lipid levels after 24 days in adenine-induced CKD rats

From: Chronic treatment of curcumin improves hepatic lipid metabolism and alleviates the renal damage in adenine-induced chronic kidney disease in Sprague-Dawley rats

Parameter Normal
Control
CKD
Control
CUR
(50 mg/kg)
CUR
(100 mg/kg)
CUR
(150 mg/kg)
Liver weight (g/100 g bw) 3.91 ± 0.09 3.61 ± 0.08 3.28 ± 0.23 3.01 ± 0.13 4.32 ± 0.50
Cholesterol (mg/g tissue) 0.38 ± 0.07 4.95 ± 1.30### 2.99 ± 0.28** 2.61 ± 0.15*** 2.53 ± 0.24***
Triglycerides (mg/g tissue) 2.55 ± 0.73 10.51 ± 1.39### 5.00 ± 1.11** 2.65 ± 0.40*** 3.73 ± 0.59***
NEFA (mg/g tissue) 0.73 ± 0.05 1.20 ± 0.06## 0.91 ± 0.11* 0.61 ± 0.07*** 0.89 ± 0.05*
  1. Values represent the mean ± SEM of 5 to 6 rats
  2. Significant difference from normal control: ##p < 0.01; ###p < 0.001
  3. Significant difference from CKD control: *p < 0.05; **p < 0.01; ***p < 0.001
  4. CKD Chronic kidney disease; CUR Curcumin; NEFA Non-esterified free fatty acids;