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Table 3 Effect of curcumin treatment on liver weight and lipid levels after 24 days in adenine-induced CKD rats

From: Chronic treatment of curcumin improves hepatic lipid metabolism and alleviates the renal damage in adenine-induced chronic kidney disease in Sprague-Dawley rats

Parameter

Normal

Control

CKD

Control

CUR

(50 mg/kg)

CUR

(100 mg/kg)

CUR

(150 mg/kg)

Liver weight (g/100 g bw)

3.91 ± 0.09

3.61 ± 0.08

3.28 ± 0.23

3.01 ± 0.13

4.32 ± 0.50

Cholesterol (mg/g tissue)

0.38 ± 0.07

4.95 ± 1.30###

2.99 ± 0.28**

2.61 ± 0.15***

2.53 ± 0.24***

Triglycerides (mg/g tissue)

2.55 ± 0.73

10.51 ± 1.39###

5.00 ± 1.11**

2.65 ± 0.40***

3.73 ± 0.59***

NEFA (mg/g tissue)

0.73 ± 0.05

1.20 ± 0.06##

0.91 ± 0.11*

0.61 ± 0.07***

0.89 ± 0.05*

  1. Values represent the mean ± SEM of 5 to 6 rats
  2. Significant difference from normal control: ##p < 0.01; ###p < 0.001
  3. Significant difference from CKD control: *p < 0.05; **p < 0.01; ***p < 0.001
  4. CKD Chronic kidney disease; CUR Curcumin; NEFA Non-esterified free fatty acids;
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BMC Nephrology

ISSN: 1471-2369

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