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Table 1 Baseline characteristics of the recipients and donors

From: Graft failure of IgA nephropathy in renal allografts following living donor transplantation: predictive factor analysis of 102 biopsies

Variables

Graft survival

(n = 76)

Graft failure

(n = 26)

p-value

Recipient age (years)

34.1 ± 8.5

39.3 ± 9.7

0.05

Recipient sex, f/m (%)

18/58 (24/76)

9/17 (35/65)

0.27

Recipient race, East Asian (%)

76 (100)

26 (100)

–

Diabetes (%)

14 (18.4)

5 (19.2)

0.93

SBP (mmHg)

146.3 ± 17.6

149.5 ± 19.4

0.92

DBP (mmHg)

74.4 ± 9.5

75.9 ± 10.5

0.50

Acute rejectiona (%)

7 (9.2)

4 (15.4)

0.38

Delayed graft function (%)

4 (5.2)

2 (7.7)

0.65

Anti-HLA antibodiesb (%)

13 (17.1)

4 (15.4)

0.84

Class I (%)

5 (6.6)

3 (11.5)

0.42

Class II (%)

13 (17.1)

2 (7.7)

0.24

HLA mismatches (A, B, or DR)

2.1 ± 1.1

1.7 ± 1.0

0.77

Therapeutic regimen

 Intravenous methylprednisolone pulsesc (%)

21 (27.6)

7 (26.9)

0.94

 Tonsillectomy (%)

10 (13.1)

6 (23.1)

0.23

 ACEIs used (%)

59 (77.6)

23 (88.5)

0.23

 Disease timed (years)

4.0 ± 3.4

5.3 ± 3.7

0.62

 Waiting timee (months)

0.8 ± 1.3

0.4 ± 0.6

0.14

 24-h urinary protein (g/24 h)

0.3 ± 0.2

0.4 ± 0.3

0.10

 Urinary RBC count (u/ml)

1.5 ± 1.8

2.0 ± 2.5

0.22

 Cholesterol (mmol/L)

5.3 ± 1.5

5.7 ± 2.5

0.36

 LDL (mmol/L)

3.4 ± 1.1

3.8 ± 1.6

0.16

 ALB (g/L)

42.0 ± 4.4

40.8 ± 4.4

0.24

 eGFRf (mL/min/1.73 m^2)g

75.2 ± 21.8

67.9 ± 20.7

0.14

 Donor age (years)

50.4 ± 8.6

49.5 ± 8.4

0.77

 Donor sex f/m (%)

53/23 (69/31)

14/12 (54/46)

0.14

 Donor race, East Asian (%)

76 (100)

26 (100)

–

  1. SBP Systolic blood pressure, DBP Diastolic blood pressure, HLA Human leukocyte antigen, ACEIs Angiotensin-converting enzyme inhibitors, RBC Red blood cell, LDL Low-density lipoprotein, ALB Albumin, eGFR Estimated glomerular filtration rate
  2. apatients with a history of acute rejection after transplantation were included if they were cured when diagnosed as IgAN
  3. bincluding donor-specific antibodies and non-donor specific antibodies
  4. cthree intravenous methylprednisolone pulses at the beginning of recurrence, but routine anti-rejection treatments after transplantation were excluded
  5. dtime from transplantation to the onset of initial symptoms
  6. etime from the onset of the initial symptoms to biopsy
  7. fbaseline eGFR after transplantation
  8. gthe volume of urine filtrated by glomeruli every 1 min in a body surface area of 1.73 square metre