Fig. 1

Representative figures of renal biopsy. a Intensive granular deposits of C3 (3 + −4+) were detected in the mesangial regions and segmental deposits along the capillary walls (immunofluorescence staining on frozen tissue, × 400). b Severe mesangial proliferation and interposition to form a lobular appearance, along with a thickening of the glomerular capillary wall with double contours (periodic acid-silver methenamine + Masson trichrome staining, × 400). c Severe mesangial proliferation with endocapillary hypercellularity and a small fibro-cellular crescent (Periodic acid staining, × 400). d Electron dense deposits in sub-endothelia, intramembranous and mesangial regions viewed by electron microscopy (× 8000)