IMN(N = 305) | FSGS-(N = 252) | FSGS+(N = 53) | P value | |
---|---|---|---|---|
Age (year) | 44.23 ± 13.95 | 43.62 ± 13.61 | 46.53 ± 15.09 | 0.195 |
Sex (female(%)) | 114/305 (37.4) | 96/252 (38.1) | 18/53 (33.9) | 0.572 |
Duration of illness (month) | 3.87 ± 4.68 | 3.46 ± 4.20 | 5.33 ± 5.93* | 0.028 |
SBP (mmHg) | 141.57 ± 19.98 | 138.03 ± 19.28 | 152.50 ± 18.46** | 0.003 |
DBP (mmHg) | 87.52 ± 13.24 | 85.68 ± 12.46 | 93.23 ± 14.23* | 0.019 |
Urine RBC/HPF | 13.92 ± 16.72 | 13.59 ± 15.98 | 15.18 ± 19.45 | 0.557 |
24-HUPRO (g/L) | 5.71 ± 3.09 | 5.60 ± 3.07 | 6.18 ± 3.19 | 0.227 |
WBC (× 109/L) | 7.64 ± 3.27 | 7.61 ± 3.14 | 7.73 ± 3.77 | 0.831 |
HGB (g/L) | 136.12 ± 17.36 | 136.40 ± 17.31 | 134.82 ± 17.74 | 0.604 |
PLT (×109/L) | 260.06 ± 61.47 | 254.64 ± 58.81 | 280.85 ± 67.45** | 0.008 |
AST (u/L) | 23.06 ± 14.14 | 21.98 ± 10.32 | 27.16 ± 23.24 | 0.138 |
ALT (u/L) | 25.55 ± 22.18 | 24.46 ± 17.49 | 29.70 ± 34.53 | 0.145 |
SOD (u/mL) | 96.36 ± 29.21 | 92.33 ± 26.43 | 110.57 ± 34.19** | 0.005 |
TP (g/L) | 45.58 ± 7.20 | 45.37 ± 6.78 | 46.34 ± 8.67 | 0.408 |
ALB (g/L) | 23.82 ± 5.26 | 23.77 ± 5.09 | 24.05 ± 6.05 | 0.723 |
GLO (g/L) | 21.85 ± 4.59 | 21.75 ± 4.30 | 22.19 ± 5.56 | 0.554 |
GLU (mmol/L) | 5.22 ± 1.41 | 5.24 ± 1.47 | 5.12 ± 1.05 | 0.628 |
BUN (mmol/L) | 5.45 ± 1.91 | 5.44 ± 1.86 | 5.49 ± 2.11 | 0.873 |
SCr (μmol/L) | 66.26 ± 19.03 | 64.21 ± 18.64 | 70.28 ± 20.25* | 0.036 |
CysC (mg/L) | 1.05 ± 0.29 | 1.05 ± 0.28 | 1.06 ± 0.33 | 0.745 |
β2-MG (mg/L) | 2.25 ± 0.80 | 2.15 ± 0.66 | 2.63 ± 1.12** | 0.010 |
RBP (mg/L) | 52.32 ± 16.87 | 51.11 ± 16.52 | 56.74 ± 17.55* | 0.047 |
Ca (mmol/L) | 2.16 ± 0.26 | 2.15 ± 0.27 | 2.18 ± 0.21 | 0.468 |
CHOL (mmol/L) | 8.85 ± 2.72 | 8.91 ± 2.76 | 8.63 ± 2.59 | 0.551 |
HDL-C (mmol/L) | 1.74 ± 0.59 | 1.75 ± 0.58 | 1.74 ± 0.62 | 0.930 |
LDL-C (mmol/L) | 5.33 ± 2.18 | 5.38 ± 2.19 | 5.14 ± 2.11 | 0.531 |
PLA2R (POSITIVE %) | 132/175 (75.4) | 98/132 (74.2) | 34/43 (79.0) | 0.523 |
IgG4 (mg/L) | 313.08 ± 248.47 | 283.81 ± 223.11 | 380.84 ± 291.16* | 0.044 |
IgG (g/L) | 5.28 ± 2.53 | 5.23 ± 2.47 | 5.50 ± 2.81 | 0.547 |
IgM (g/L) | 1.09 ± 0.54 | 1.11 ± 0.56 | 0.99 ± 0.42 | 0.191 |
IgA (g/L) | 2.20 ± 0.87 | 2.19 ± 0.79 | 2.22 ± 1.14 | 0.912 |
C3 (g/L) | 1.16 ± 0.25 | 1.16 ± 0.25 | 1.17 ± 0.25 | 0.804 |
C4 (g/L) | 0.29 ± 0.08 | 0.28 ± 0.08 | 0.29 ± 0.07 | 0.528 |
C1q (mg/L) | 207.13 ± 41.49 | 206.48 ± 40.21 | 210.11 ± 47.18 | 0.612 |