Table 2 Histopathologic Parameters at the Time of Renal Biopsy
FSGS-(N = 252) | FSGS+(N = 53) | P value | |
|---|---|---|---|
Pathological stage(%) | |||
I | 136/252 (53.9) | 23/53 (43.4) | 0.161 |
II | 114/252 (45.3) | 30/53 (56.6) | 0.132 |
III + IV | 2/252 (0.8) | 0 | |
Tissue IgG | 2.77 ± 0.63 | 2.63 ± 0.82 | 0.370 |
Tissue IgM | 0.45 ± 0.81 | 0.43 ± 0.75 | 0.967 |
Tissue IgA | 2.30 ± 0.81 | 2.13 ± 1.36 | 0.597 |
Tissue C3 | 1.47 ± 1.08 | 1.31 ± 1.00 | 0.364 |
Tissue Fib | 0.53 ± 1.22 | 0.13 ± 048* | 0.025 |
Tissue C1q | 0.80 ± 1.17 | 0.53 ± 0.77 | 0.146 |
Pathological characteristics | |||
Glomerular sclerosis | 105/252 (40.5.) | 30/53 (56.6)* | 0.047 |
Mesangial proliferative lesions | 67/252 (26.6) | 30/53 (56.6)** | 0.000 |
Crescents | 2/252 (0.8) | 1/53 (1.8) | 0.464 |
Endothelial hyperplasia | 5/252 (1.9) | 6/53 (11.3)** | 0.001 |
Acute tubular lesions | 12/252 (4.7) | 7/53 (13.2)* | 0.021 |
Chronic tubular lesions | 15/252 (5.9) | 17/53 (32.0)** | 0.000 |
Inflammatory cell infiltration | 8/252 (3.2) | 4/53 (7.5) | 0.137 |
Small vessel lesions | 57/252 (22.6) | 23/53 (43.4)** | 0.002 |