Fig. 4

Number of patients identified as requiring referral to a nephrologist to find one ESKD case and sensitivity associated with a range of thresholds of the Recalibrated Pooled KFRE SEA equation for 5-year and 2-year risk of end-stage kidney disease. The figure shows number of patients identified as requiring referral to a nephrologist to find one ESKD case and sensitivity associated with a range of thresholds of Recalibrated Pooled KFRE SEA equation for a) 5-year and b) 2-year risk of end-stage kidney disease applied on the primary care patients with CKD from nine primary care clinics. The grey bar represents number of patients identified as requiring referral using each KFRE threshold as referral decision point to find one ESKD case, the solid line represents sensitivity of each KFRE threshold, and the dotted lines represent the upper and lower bound of 95% confidence interval of sensitivity. The Recalibrated Pooled KFRE SEA equation for 5-year ESKD risk was calculated as: 1–0.8362 ^ exp. (− 0.2245 × (age/10–7.036) + 0.3212 × (male - 0.5642) - 0.4553 × (eGFR/5–7.222) + 0.4469 × (lnACR - 5.137)). The Recalibrated Pooled KFRE SEA equation for 2-year ESKD risk was calculated as: 1–0.8976 ^ exp. (− 0.2245 × (age/10–7.036) + 0.3212 × (male - 0.5642) - 0.4553 × (eGFR/5–7.222) + 0.4469 × (lnACR - 5.137)). Abbreviation: ACR; albumin-to-creatinine ratio; CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; ESKD, end-stage kidney disease; KFRE, Kidney Failure Risk Equation; SEA, Southeast Asia