Variables | SPK (n = 22) | KTA (n = 20) | P-value |
---|---|---|---|
Donor | |||
Age, years | 50.5 ± 4.5 | 61.7 ± 6.7 | < 0.01 |
Gender | |||
Male | 16 (72.7%) | 16 (80%) | 0.580 |
Female | 6 (27.3%) | 4 (20%) | |
BMI, kg/m2 | 27.8 ± 3.9 | 27.7 ± 2.7 | 0.884 |
Recipient | |||
Age, years | 30.7 ± 12.7 | 60.4 ± 15.8 | < 0.01 |
Gender | |||
Male | 12 (54.5%) | 8 (40%) | 0.346 |
Female | 10 (45.5%) | 12 (60%) | |
BMI, kg/m2 | 23.3 ± 2.7 | 24.8 ± 1.8 | 0.079 |
Duration of IDDM, years | 27.8 ± 7.9 | 19.2 ± 9.5 | < 0.01 |
Duration of dialysis, months | 3.8 ± 3.1 | 5.7 ± 1.9 | 0.05 |
Blood pressure, mmHg | |||
Systolic | 145 ± 10 | 148 ± 5 | 0.07 |
Diastolic | 86 ± 8 | 91 ± 5 | 0.05 |
Antihypertensive drugs, n | 3.1 ± 1.2 | 2.6 ± 1.6 | 0.237 |
Arterial obstructive disease | |||
Yes | 17 (77%) | 8 (40%) | 0.015 |
No | 5 (23%) | 12 (60%) | |
Coronary heart disease | |||
Yes | 17 (77.3%) | 19 (95%) | 0.101 |
No | 5 (22.7%) | 1 (5%) | |
Time on waiting list, months | 14.5 ± 16.9 | 16.1 ± 28.1 | 0.822 |
Pre-emptive transplant | 9 (41%) | 1 (1%) | < 0.01 |
Immunosuppression | |||
Induction therapy | |||
ALG/ATG | 15 (68.2%) | 4 (20%) | 0.006 |
IL2-RA | 5 (22.7%) | 9 (45%) | |
None | 2 (4.8%) | 7 (35%) | |
CNI | |||
Tacrolimus | 22 (100%) | 19 (95%) | 0.288 |
Cyclosporin | 0 (0%) | 1 (5%) | |
AP drug | |||
MMF | 19 (86.4%) | 17 (85%) | 0.049 |
SRL | 3 (13.6%) | 0 | |
Multiple | 0 | 0 | |
None | 0 | 3 (15%) |