Table 2 Associations between tertiles of three microRNAs and chronic kidney disease (eGFR < 60)
| Â | Crude model | Fully adjusted model | ||||
|---|---|---|---|---|---|---|
microRNA | CKD (%) | OR (95%CI) | p | OR (95%CI) | p | |
miR-126 | Low (n = 457) | 98 (21.4%) | Reference | Reference | ||
Middle (n = 471) | 76 (16.1%) | 0.71 (0.51–0.98) | 0.04 | 0.74 (0.52–1.06) | 0.11 | |
High (n = 457) | 55 (12.0%) | 0.50 (0.35–0.72) | < 0.001 | 0.67 (0.45–0.98) | 0.04 | |
miR-197 | Low (n = 457) | 100 (21.9%) | Reference | Reference | ||
Middle (n = 471) | 75 (15.9%) | 0.68 (0.48–0.94) | 0.02 | 0.72 (0.50–1.02) | 0.07 | |
High (n = 457) | 54 (11.8%) | 0.48 (0.33–0.68) | < 0.001 | 0.67 (0.46–0.99) | 0.05 | |
miR-223 | Low (n = 457) | 110 (24.1%) | Reference | Reference | ||
Middle (n = 471) | 75 (15.9%) | 0.59 (0.43–0.83) | 0.002 | 0.69 (0.49–0.98) | 0.04 | |
High (n = 457) | 44 (9.6%) | 0.34 (0.23–0.49) | < 0.001 | 0.53 (0.35–0.79) | 0.002 | |