A comparison between the combined effect of calcium carbonate with sucroferric oxyhydroxide and other phosphate binders: an in vitro and in vivo experimental study

Table 5 Combined effect expected in clinical practice

Drugs	pH 2 (Normal condition)	pH 7 (Condition simulating increased gastrointestinal pH)
CC + PA21	↑	↑
CC + LC	↑	↓
CC + FC	↓	–

CC Calcium carbonate, LC Lanthanum carbonate hydrate, FC Ferric citrate hydrate. ↑: Additive effect, ↓: Antagonistic effect, −: The combined effect was not evaluated because the main effect of ferric citrate hydrate was not observed

ISSN: 1471-2369