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Table 1 Baseline characteristics

From: Modified regional citrate anticoagulation is optimal for hemodialysis in patients at high risk of bleeding: a prospective randomized study of three anticoagulation strategies

Factors

Part one

Part two

RCA-one (n = 39)

RCA-two (n = 38)

P value

Saline (n = 31)

RCA-two (n = 33)

P value

Male, n (%)

18 (46.15)

19 (50.00)

0.903

18 (58.06)

16 (48.48)

0.443

Age, median (IQR), years

55 (50–63)

56 (50–64)

0.988

56 (41–70)

52 (37–65)

0.459

Weight, median (IQR), kg

59.5 (47.0–63.0)

53.7 (50.8–60.0)

0.639

59.5 (52.0–63.3)

56.4 (50.0–60.0)

0.204

Diabetes mellitus, n (%)

5 (12.82)

6 (15.79)

0.709

4 (12.90)

8 (24.24)

0.245

Access type-AV fistula, n/catheter, n

20/19

30/8

0.011

19/12

23/10

0.479

Causes of high risk of bleeding

  

0.389

  

0.113

Perioperation, n (%)

23 (58.97)

26 (68.42)

 

15 (48.39)

10 (30.30)

 

Hemorrhage, n (%)

16 (41.03)

12 (31.58)

 

12 (38.71)

19 (57.58)

 

Blood flow rate, median (IQR), ml/min

200 (200–210)

210 (200–220)

0.089

200 (200–220)

200 (200–220)

0.946

Ultrafiltration, mean ± sd, L

1.8 ± 0.9

2.1 ± 0.9

0.334

1.97 ± 0.79

1.90 ± 0.75

0.728

Rate of Ultrafiltration, mean ± sd, L/h

0.7 ± 0.2

0.7 ± 0.2

0.294

0.9 ± 0.3

0.7 ± 0.2

0.006

Pre-dialysis SBP, mean ± sd, mmHg

155.41 ± 25.34

149.56 ± 24.09

0.348

150.52 ± 22.98

152.27 ± 24.41

0.768

Pre-dialysis DBP, mean ± sd, mmHg

79.78 ± 11.09

79.25 ± 13.08

0.862

79.52 ± 15.13

83.58 ± 18.12

0.336

Hemoglobin, g/L

87.0 (80.0–92.50)

95.5 (83.0–110.0)

0.023

97.0 (93.0–109.0)

82. 0 (78.0–94.0)

0.007

Blood platelets, 109/L

195.5 (147.0–262.5)

194.5 (130.5–258.5)

0.847

173.0 (157.0–204.0)

216.0 (200.0–233.0)

0.082

Prothrombin time, second

13.7 (13.3–14.5)

13.8 (13.3–14.7)

0.893

13.6 (13.1–14.4)

13.3 (12.4–14.2)

0.435

Activated partial thromboplastin time, second

41.0 (36.8–43.2)

38.6 (36.5–40.3)

0.106

39.7 (36.8–41.5)

40.2 (37.0–43.2)

0.295

pH value

7.37 (7.34–7.39)

7.41 (7.38–7.42)

0.001

7.35 (7.33–7.39)

7.40 (7.36–7.42)

0.001

  1. Abbreviations: VP venous pressures, TMP transmembrane pressures, AP arterial pressures, DBP diastolic blood pressure, SBP Systolic blood pressure, AV fistula arterial- venous fistula, IQR interquartile range, n patient, sd Standard deviation. Categorical variables were described as frequencies (n) or percentages (%) and analyzed with Pearson’s chi-square or Fisher’s exact test. The Kolmogorov-Smirnov test was used to check the normal distribution of all continuous data. Parametric continuous parameters are expressed as mean ± standard deviation and analyzed with unpaired Student’s t-tests; nonparametric continuous parameters are expressed as medians (interquartile range, IQR) and analyzed with the Wilcoxon test
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BMC Nephrology

ISSN: 1471-2369

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