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Table 1 Patient characteristics at baseline

From: Intradialytic hypotension is an important risk factor for critical limb ischemia in patients on hemodialysis

 

All

(N = 147)

IDH (−)

(N = 97)

IDH (+)

(N = 50)

Age (y)

70.9 ± 11.1

71.1 ± 11.0

70.6 ± 11.4

Male/female

90/57

61/36

29/21

Time since starting HD (months)

112 (68–167)

121 (74–173)

108 (60–157)

Diabetes mellitus

63 (42.9)

35 (36.1)

28 (56.0)

Hypertension

131 (89.1)

84 (86.6)

47 (94.0)

Smoking

60 (40.8)

40 (41.2)

20 (40.0)

History

 CVD (%)

55 (37.4)

31 (32.0)

24 (48.0)

 PAD (%)

16 (10.9)

6 (6.1)

10 (20.0)

Medication

 Antiplatelet agents (%)

88 (59.8)

57 (58.8)

31 (62.0)

 ARB (%)

95 (64.6)

61 (62.9)

34 (68.0)

 ACEI (%)

7 (4.8)

5 (5.2)

2 (4.0)

 CCB (%)

83 (56.5)

59 (60.8)

24 (48.0)

 β-blocker (%)

44 (29.9)

31 (32.0)

13 (26.0)

Characteristics on dialysis

 IDWG (%)

3.91 ± 1.39

3.74 ± 1.36

4.25 ± 1.41

 Systolic BP (mmHg)

142.3 ± 19.9

141.6 ± 18.3

143.6 ± 23.0

 Diastolic BP (mmHg)

74.7 ± 13.2

75.6 ± 12.1

72.9 ± 15.3

 Blood flow rate (mL/min)

213 ± 33

215 ± 33

208 ± 32.8

 Kt/V urea

1.51 ± 0.26

1.50 ± 0.27

1.52 ± 0.25

 Dialyzer: PS/PES

105 (71.4%)

74 (76.3)

31 (62.0)

 Dialyzer: cellulose triacetate

35 (23.8%)

18 (18.6)

17 (34.0)

 IDH

50 (34.5%)

0 (0%)

50 (100%)

Laboratory data

 Albumin (g/dL)

3.68 ± 0.29

3.72 ± 0.24

3.58 ± 0.36

 Corrected Calcium (mg/dL)

8.33 ± 0.68

8.32 ± 0.68

8.35 ± 0.70

 Phosphate (mg/dL)

5.28 ± 1.02

5.20 ± 0.96

5.44 ± 1.13

 Intact PTH (pg/mL)

204.3 ± 126.9

201.2 ± 119.7

210.4 ± 141.0

 HDL-C (mg/dL)

48.5 ± 13.8

49.5 ± 14.5

46.6 ± 12.4

 LDL-C (mg/dL)

78.3 ± 23.2

81.0 ± 23.2

73.3 ± 22.8

 Glycoalbumin (%)

17.9 ± 4.7

17.5 ± 4.4

18.9 ± 5.2

 Hemoglobin (g/dL)

11.1 ± 0.79

11.1 ± 0.82

11.2 ± 0.72

 β2-microglobulin (mg/L)

27.2 ± 5.10

26.8 ± 5.15

28.0 ± 4.95

  1. The data are presented as the mean ± standard deviation, median (interquartile range), or number (percentage). Abbreviations: ARB angiotensin receptor blocker; ACEI angiotensin-converting enzyme inhibitor; BP blood pressure; CCB calcium channel blocker; CVD cardiovascular disease; HD hemodialysis; HDL-C high-density lipoprotein cholesterol; IDH intradialytic hypotension; IDWG interdialytic weight gain; LDL-C low-density lipoprotein cholesterol; PAD peripheral arterial disease; PES polyethersulfone; PS polysulfone; PTH parathyroid hormone