Table 1 Clinical profiles and pathological findings of PSAGN with “ANCA-negative” vasculitis
Age/Sex | Cre (mg/dL) | Alb (g/dL) | WBC (/μL) | CRP (mg/dL) | C3 (mg/dL) | C4 (mg/dL) | ASO (IU/mL) | Culture test (specimen) | Onset to biopsy (day) | Crescent formation | Interstitial Inflammation | Vasculitis lesion | IF | hump | NAPlr staining | Treatment | Reference |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
71/M | 3.28 | 3.6 | 14,300 | 15.92 | 42 | 27 | 520 | negative (blood, urine, joint fluid) | 7 | + | + | PTCitis, venulitis, arteriolitis in the glomerular hilus | no deposition | – | + (glomeruli) | corticosteroids hemodialysis | Our case |
12/M | 3.15 | 1.92 | 24,600 | 15.74 | 103 | 14 | 101 | negative (blood) | 13 | – | + | Fibrinoid necrosis in arteriole | no deposition | – | + (glomeruli) | corticosteroids hemodialysis antibiotics | [13] |
72/M | 7.92 | NAa | NA | NA | 59 | 26 | 340 | NA | NA | – | + | PTCitis | C3 (capillary, mesangium) | NA | NA | corticosteroids hemodialysis | [14] |
53/M | 11.8 | NA | NA | > 15.00 | 41 | 7 | 1150 | negative (synovial fluid, throat) | NA | – | + | Fibrinoid necrosis, hyaline thrombi in arteriole | IgG, C3 (capillary) | + | NA | corticosteroids antibiotics | [15] |