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Table 4 Cox regression analyses-adjusted HR for for primary endpoint

From: Long-term predictive value of acute kidney injury classification in diffuse proliferative lupus nephritis with acute kidney injury

variables

HR

95%confidence intervals

P-value

AKI stage

3.8

2.1–6.7

< 0.001

C3 > 0.4 mg/dl

0.7

0.2–2.1

0.49

MP pulse treatment

0.8

0.2–2.5

0.68

INS/PRN LN type IV + V

0.9

0.7–1.2

0.44

INS/PRN active+chonic lesion

1.1

0.3–3.5

0.89

great crescent> 30%

2.1

1.2–3.6

0.008

mBP > 115 mmHg

2.6

0.9–7.7

0.081

Hb < 8.0 g/dl;mean ± SD)

4.8

1.6–14.0

0.005

Proteinuria> 3.0 g/d

5.1

1.5–17.1

0.008

  1. AKI acute kidney injury, C3 serum complement component 3, MP methylprednisolone, LN lupus nephritis; great crescent, is one of those extracapillary lesions that involves > 50% of the circumference of Bowman’s capsule; great crescents ≥30%, refers to patients with > 30% of the glomeruli containing great crescents; mBP mean blood presure, Hb hemoglobin