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Table 4 Odds ratios from multinomial logistic regression models for CKD stage 3 and stages 4–5 per μm increase in thickness of retinal layers supplied by the retinal microvasculature

From: Association of reduced inner retinal thicknesses with chronic kidney disease

ETDRS segment

Right eye

Left eye

CKD stage 3 (vs. stage 1–2)

CKD stage 4–5 (vs. stage 1–2)

CKD stage 3 (vs. stage 1–2)

CKD stage 4–5 (vs. stage 1–2)

OR

95% CI

p

OR

95% CI

p

OR

95% CI

p

OR

95% CI

p

Nerve fibre layer

 N1

0.99

(0.86, 1.14)

0.88

0.88

(0.74, 1.05)

0.15

1.01

(0.90, 1.13)

0.93

1.00

(0.90, 1.11)

0.95

 S1

1.05

(0.96, 1.16)

0.27

1.00

(0.90, 1.11)

0.97

1.03

(0.94, 1.13)

0.52

0.99

(0.89, 1.10)

0.85

 T1

0.83

(0.64, 1.06)

0.14

1.04

(0.96, 1.13)

0.35

0.95

(0.77, 1.17)

0.63

1.14

(0.96, 1.36)

0.14

 I1

0.97

(0.87, 1.08)

0.58

0.94

(0.84, 1.06)

0.31

1.02

(0.92, 1.13)

0.70

1.00

(0.90, 1.11)

0.94

Ganglion cell layer

 N1

1.02

(0.96, 1.09)

0.48

0.93

(0.87, 1.00)

0.04*

1.00

(0.94, 1.07)

0.98

0.94

(0.87, 1.01)

0.08

 S1

1.02

(0.95, 1.09)

0.60

0.92

(0.86, 0.99)

0.02*

1.01

(0.94, 1.09)

0.75

0.95

(0.88, 1.03)

0.18

 T1

1.01

(0.94, 1.08)

0.87

0.89

(0.82, 0.97)

0.01*

1.01

(0.95, 1.07)

0.74

0.93

(0.87, 0.99)

0.02*

 I1

1.02

(0.95, 1.10)

0.57

0.90

(0.83, 0.96)

0.004*

1.03

(0.96, 1.10)

0.47

0.90

(0.84, 0.97)

0.004*

Inner plexiform layer

 N1

1.01

(0.92, 1.11)

0.83

0.91

(0.82, 1.00)

0.04*

0.99

(0.91, 1.09)

0.90

0.90

(0.82, 1.00)

0.04*

 S1

1.01

(0.92, 1.12)

0.78

0.89

(0.80, 0.99)

0.03*

0.99

(0.89, 1.10)

0.81

0.88

(0.78, 0.99)

0.03*

 T1

1.00

(0.90, 1.11)

0.96

0.87

(0.78, 0.98)

0.02*

1.03

(0.93, 1.13)

0.61

0.89

(0.80, 0.99)

0.03*

 I1

1.01

(0.90, 1.12)

0.92

0.85

(0.76, 0.96)

0.01*

1.02

(0.92, 1.14)

0.66

0.82

(0.73, 0.93)

0.002*

Inner nuclear layer

 N1

0.91

(0.82, 1.02)

0.10

0.9

(0.79, 1.02)

0.11

0.90

(0.81, 1.01)

0.07

0.96

(0.86, 1.06)

0.42

 S1

0.92

(0.83, 1.02)

0.11

0.9

(0.80, 1.01)

0.08

0.92

(0.84, 1.01)

0.09

0.88

(0.79, 0.97)

0.01*

 T1

0.91

(0.80, 1.03)

0.14

0.87

(0.75, 1.00)

0.06

0.93

(0.83, 1.03)

0.17

0.88

(0.78, 0.99)

0.03*

 I1

0.96

(0.86, 1.06)

0.42

0.96

(0.84, 1.08)

0.49

0.93

(0.84, 1.03)

0.16

0.89

(0.79, 1.00)

0.06

  1. ETDRS Early Treatment Diabetic Retinopathy Study, OR Odds ratio, SD Standard deviation, CI Confidence interval, F Fovea, S1 Superior segment 1, N1 Nasal segment 1, I1 Inferior segment 1, T1 Temporal segment 1.*significant values. Adjustment for age, mean arterial blood pressure, diabetes status, low-density lipoprotein, body mass index, and sex