From: Furosemide stress test and interstitial fibrosis in kidney biopsies in chronic kidney disease
Variable | Kidney allograft (n = 30) | Native kidneys (n = 54) | Total group (n = 84) | P |
---|---|---|---|---|
Age (y) | 34.6 ± 14.8 | 40.9 ± 15 | 38.6 ± 15.1 | 0.071 |
Gender (M/F) N (%) | 18 (60) / 12 (40) | 19 (35.2) / 35 (64.8) | 37 (44) / 47 (56) | 0.028* |
Baseline eGFR (ml/min/1.73m2) | 47.2 ± 26.8 | 73.2 ± 45.6 | 63.9 ± 41.6 | 0.001* |
Serum Albumin (g/dl) | 3.8 ± 0.7 | 2.9 ± 0.8 | 3.2 ± 0.9 | 0.000* |
Urinary protein excretion (g/g creatinine) | 1.62 ± 2.63 | 4.55 ± 4.52 | 3.47 ± 4.16 | 0.002* |
Diabetes Mellitus N (%) | 23 (76.7) | – | 23 (76.7) | 0.000* |
Hypertension N (%) | – | 20 (37) | 20 (37) | 0.000* |
Systemic lupus erythematosus N (%) | 1 (3.3) | 21 (38.9) | 22 (26.2) | 0.000* |
Interstitial Fibrosis N (%) | ||||
Grade I | 13 (43.3) | 32 (59.3) | 45 (53.6) | 0.003* |
Grade II | 16 (53.3) | 11 (20.4) | 27 (32.1) | 0.003* |
Grade III | 1 (3.3) | 11 (20.4) | 12 (14.3) | 0.003* |
Combined | 25.3 ± 15.4 | 28.7 ± 22.3 | 27.5 ± 20.1 | 0.409 |