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Table 2 Correlation of the GFR-change with pretransplant, peri- and posttransplant clinical factors which were considered as candidate variables in the multivariable modeling

From: Long-term renal graft outcome after parathyroidectomy - a retrospective single centre study

 

eGFR change at 3 months post para-thyroidectomy

P value

eGFR change at 12 months post para-thyroidectomy

P value

Recipient at transplantation

 Age

0.281

0.055

0.153

0.303

 Gender (male/female)

−19.40; −8.22

0.002

12.93; −6.83

0.053

 Hyperparathyroidism before transplantation, yes; no

−14.10; −21,54

0.414

−10.59; −13.93

0.414

 Parathyroidectomy before transplantation, yes; no

−16.87; −11.29

0.568

−14.78; −9.88

0.158

 Time on dialysis before transplantation

−0.078

0.603

− 0.195

0.189

 Re-transplanted patients, 2nd or 3rd transplantation; 1st transplantation

−20.34; − 11.68

0.372

−13.93; − 10.23

0.535

 Body weight at transplantation

−0.277

0.065

−0.265

0.078

 Body mass index at transplantation

−0.146

0.340

−0.239

0.114

Early post-transplantation course

 Delayed graft function, yes; no

−12.42; −16;57

0.924

−10.23; −11.76

0.505

 Best eGFR in the first 6 weeks post- transplantation

−0.542

< 0.001

−0.239

0.055

Post-transplant-related factors

 Last serum calcium before parathyroidectomy

0.190

0.200

0.290

0.048

 Mean serum calcium within the first 6 months after transplantation

0.143

0.338

0.220

0.137

 Last serum phosphate before parathyroidectomy

−0.034

0.832

−0.132

0.412

 Mean serum phosphate within the first 6 months after transplantation

0.031

0.836

−0.115

0.441

 Last iPTH before parathyroidectomy

−0.226

0.127

−0.409

0.004

 Mean iPTH within the first 6 months after transplantation

−0.146

0.328

−0.278

0.058

 iPTH change after parathyroidectomy

0.199

0.190

0.374

0.011

 Months between transplantation and parathyroidectomy

0.198

0.183

0.193

0.194

 eGFR 6 weeks after transplantation

−0.464

0.001

− 0.207

0.162

 eGFR 3 months after transplantation

−0.524

< 0.001

− 0.227

0.124

 eGFR 6 months after transplantation

− 0.373

0.010

−0.129

0.386

 eGFR 3 months before parathyroidectomy

−0.501

< 0.001

−0.361

0.013

 Last eGFR before parathyroidectomy

−0.500

< 0.001

−0.398

0.006

 eGFR change before parathyroidectomy

−0.050

0.741

−0.159

0.285

 Nephrocalcinosis at biopsy, yes; no

−16.45; −8.8

0.461

−11.5; −7.9

0.242

 Rejections until parathyroidectomy yes; no

−14.2; −10.5

0.749

−7.7; − 11.3

0.701

  1. The change in eGFR 3 months and 12 months after parathyroidectomy was calculated individually for each patient as the difference between the post-parathyroidectomy value and the eGFR before parathyroidectomy, with negative values representing a loss of eGFR. PTH change: decrease in iPTH is defined as negative value. Shown are r values for continuous factors and grouped medians for categorical variables. eGFR estimated glomerular filtration rate, iPTH intact parathormone
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BMC Nephrology

ISSN: 1471-2369

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