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Table 5 Clinical details of 10 non-pregnant dialysis patients with hCG concentrations > 5 mIU/ml and two pregnant dialysis patients

From: Exclusion of pregnancy in dialysis patients: diagnostic performance of human chorionic gonadotropin

Patient No.

Age categories (years)

BMI categories (kg/m2)

PD or HD

ESRD vintage (years)

Pregnancies (count)

Live births (count)

Current menstrual cycle (y/n/u/i)

Cycle day of blood sampling

hCG (mIU/ml)

LH (mIU/ml)

FSH (mIU/ml)

AMH (ng/ml)

No, functional, pre-, or true menopause (N, F, P, T)

Comment

Non-pregnant dialysis patients

 1

45.0–50.0

18.5–24.9

HD

23.1

5

3

n

–

6.00

83.4

142

< 0.08a

T

Infertile, elevated FSHb

 2

45.0–50.0

18.5–24.9

HD

2.30

11

8

n

–

6.00

187

172

< 0.08a

T

Infertile, elevated FSH

 3

45.0–50.0

18.5–24.9

HD

0.13

1

1

n

–

21.0

125

58.3

< 0.08a

T

Infertile, elevated FSH

 4

45.0–50.0

< 18.5

HD

1.53

0

0

n

–

24.0

< 0.10

1.00

< 0.08a

T

Infertilec

 5

45.0–50.0

< 18.5

HD

2.27

0

0

n

–

25.0

> 200

> 200

< 0.08a

T

Infertile, elevated FSHb

 6

20.0–24.9

18.5–24.9

HD

19.6

0

0

r

u

7.00

1.30

3.10

3.89a

N

Potentially fertile, high prolactin, hCG decreased at follow-up

 7

20.0–24.9

18.5–24.9

HD

0.97

0

0

r

1

9.80

4.60

65.2

< 0.08a

P

Infertile, elevated FSH

 8

45.0–50.0

25.0–29.9

HD

25.1

1

1

n

–

7.90

116

105.8

0.01

T

Infertile, elevated FSH

 9

45.0–50.0

< 18.5

HD

1.10

0

0

n

–

7.00

< 0.10

0.90

0.10

T

Infertilec

 10

45.0–50.0

≥30

HD

1.63

1

1

n

–

15.0

82.3

69.7

0.01

T

Infertile, elevated FSHb

Pregnant dialysis patients

              

11

25.0–29.9

≥30

HD

0.16

4

3

–

–

53454d

< 0.10

< 0.10

3.64

N

Fertile, delivery of a healthy child

12

45.0–50.0

25.0–29.9

HD

2.08

10

2

–

–

58.0e

13.7

17.1

0.05

N

Fertile, missed abortion (1st trimester)

  1. No. number, BMI body mass index, HD hemodialysis, PD peritoneal dialysis, ESRD end-stage renal disease, hCG human chorionic gonadotropin, LH luteinizing hormone, FSH follicle stimulating hormone, AMH anti-Müllerian hormone, y yes, n no, u unknown, i irregular, N no, F functional, P pre, T true
  2. a, AMH measured by ELISA (Beckman-Coulter); b, received a kidney transplant during follow-up and remained infertile with elevated serum hCG concentration; c, low LH & FSH related to hypogonadotropic hypogonadism caused by anorexia; d, week 16 + 4 of gestation; e, week 4 + 1 of gestation