Table 1 Clinical and demographic features of IgAN patients and healthy controls
|  | Healthy group (n = 18) | IgAN group (n = 17) | P-value |
|---|---|---|---|
Sex (Female/Male) | 4/14 | 3/14 | 0.735 |
Age (years) | 49.72 ± 8.39 | 44.76 ± 10.53 | 0.132 |
BMI (kg/m2) | 23.16 ± 1.39 | 22.18 ± 2.09 | 0.108 |
CysC (mg/L) | 0.55 ± 0.08 | 0.82 ± 0.43 | 0.011 |
BUN (mmol/L) | 4.88 ± 0.99 | 5.64 ± 2.29 | 0.208 |
Scr (μmol/L) | 56.35 ± 8.65 | 101.43 ± 87.04 | 0.036 |
eGFR (ml/min/1.73m2) | 107.13 ± 12.52 | 83.16 ± 32.49 | 0.006 |
uACR (mg/g) | 9.61 ± 3.00 | 949.49 ± 814.11 | 0.000 |
GLU (mmol/L) | 5.03 ± 0.54 | 5.08 ± 0.51 | 0.764 |
TC (mmol/L) | 4.43 ± 0.71 | 4.84 ± 0.99 | 0.160 |
TG (mmol/L) | 1.29 ± 0.23 | 1.54 ± 0.62 | 0.119 |
CRP | 0.47 ± 0.29 | 1.12 ± 1.17 | 0.030 |
Frequency of pathologic features (percentages) in 17 biopsies scored according to Oxford Classification | |||
mesangial hypercellularity (M) M0 = 12% M1 = 88% | |||
endocapillary hypercellularity (E) E0 = 88% E1 = 12% | |||
segmental glomerulosclerosis (S) S0 = 71% S1 = 29% | |||
tubular atrophy/interstitial fibrosis (T) T0 = 76% T1 = 18% T2 = 6% | |||