Skip to main content
Fig. 3 | BMC Nephrology

Fig. 3

From: HLA-G14bp ins/del polymorphism and post-transplant weight gain in kidney transplantation: potential implications beyond tolerance

Fig. 3

Pre/post-transplant measurements of BMI (kg/m2) and HLA-G14bp ins/del genotypes in kidney transplant recipients: a and b: total recipients; b recessive model: significantly increased BMI in HLA-G14bp ins/ins, as compared with ins/del + del/del recipients, at 3 and 4 years (p = 0.033 and 0.044, respectively); using repeated-measures ANOVA, it was observed a significant main effect of HLA-G14bp genotypes on BMI (p = 0.049), with no significant interaction between BMI and HLA-G14bp genotypes; c and d: pre-post transplant BMI when pre-transplant obese patients (BMI > 30) were excluded from the analysis (n = 154); d recessive model: significant pre-post transplant weight gain in both ins/ins and ins/del + del/del carriers (p < 0.005) and significant interaction between BMI and HLA-G14bp genotypes (F = 4.45, p = 0.007); after transplantation, only carriers of ins/ins genotype had significantly increased BMI between 1 to 2 (p = 0.01), 3 (p = 0.001), 4 (p = 0.008) and 5 (p < 0.001) years after transplant. Pre-tx = pre-transplant

Back to article page