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Fig. 5 | BMC Nephrology

Fig. 5

From: Experimental rat model for acute tubular injury induced by high water hardness and high water fluoride: efficacy of primary preventive intervention by distilled water administration

Fig. 5

Histopathological examination of kidney tissues stained with hematoxylin-eosin (HE) under light microscope (200X). a Control rats showing normal rat kidney with normal tubular brush-borders (BB); b tubular brush-borders loss less than 25% of tubular cells and integrity of basal membrane in test water treated rats for 60 days; c loss of tubular brush-border in more than 25% of tubular cells and thickened basal membrane in test water treated rats for 90 days; d Distilled water treated control rats with normal morphology of kidney; improved tubule architecture in distilled water treated rats for 60 (e) and 90 days (f)

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